Psychiatric disorders are highly genetically correlated, but little research has been conducted on the genetic differences between disorders. We developed a new method (case–case genome-wide association study; CC-GWAS) to test for differences in allele frequency between cases of two disorders using ...
Log In Sign Up Subjects Social sciences What is it called when two different alleles of a gene are expressed?Question:What is it called when two different alleles of a gene are expressed?Genes:Genes are segments on DNA that contain the instructions to produce proteins. Humans ...
Duplicated loci, for example those associated with major histocompatibility complex (MHC) genes, often have similar DNA sequences that can be coamplified with a pair of primers. This results in genotyping difficulties and inaccurate analyses. Here, we present a method to assign alleles to ...
A standard competition ELISA was used to address whether the antibody response can be further focused on shared epitopes by exclusively boosting these common determinants through immunization of rabbits with different Pf AMA1 alleles in sequence. The in vitro parasite growth inhibition assay was used ...
countries (or regions and organizations) were analyzed using SSR marker.【Result】With 34 SSR primers which were polymorphic and uniformly distributed in rice genome, a total of 198 alleles were detected among these improved varieties with the average number of alleles per pair of primers of ...
A. HULTN - 《Annals of Human Genetics》 被引量: 361发表: 1985年 The choice in meiosis – defining the factors that influence crossover or non-crossover formation Meiotic crossovers are essential for ensuring correct chromosome segregation as well as for creating new combinations of alleles for ...
If these numbers reflect the actual protein levels, and every allele is expressed at an equal level, it would mean that 7% mutated CALM1 (one of six alleles) is sufficient to cause heart arrhythmia (see also part 4.1). In this section we will review human public RNA-seq data from high...
The clear and reproducible bands were considered for counting alleles in the ISSR analysis. The ISSR amplificon profile for each of the obtained mutants and control was assessed in the same loci by the precent or absence of the band. A binary data matrix was generated as the presence of the...
The mean value of number on alleles(Na) of CSC, AQC, JXC, JJC, SSC, SJC, RCC, HJC and HC was 4.67, 5.22, 5.33, 5.00, 4.89, 4.78, 4.89, 4.67 and 2.56, respectively. The mean value of expected heterozygosity(He) was 0.6397, 0.6543, 0.6831, 0.6356, 0.6737, 0.6483, 0.6664, 0.7129...
The expression patterns of the two fly MMPs are very different, and genetic analysis with over a dozen MMP alleles, including conditional temperature-sensitive alleles, has demonstrated some distinct and some shared functions for each MMP. For example, Mmp1 is required for tube elongation and ...