Mononuclear cells were isolated from peripheral blood and bone marrow of patients with RA and OA undergoing hip replacement. Sodium citrate was used as an anticoagulant. To assess cell phenotypes, specific monoclonal antibodies against: CD3, CD19, CD20, CD4, CD8, CD16, CD56, CD38, CD27, CD25...
Commercial autologous therapies, as well as those still in clinical development, have consistently demonstrated an excellent safety profile and durable responses. Many have validated targets such as CD20 and CD19 to treat high-risk B-cell non-Hodgkin lymphomas, chronic lymphocytic leukemia, and other...