Topologically associating domains (TADs) are critical structural units in three-dimensional genome organization of mammalian genome. Dynamic reorganizations of TADs between health and disease states are associated with essential genome functions. However
Malware Classification Method via Binary Content Comparison RACS 2012 link Binary function clustering using semantic hashes ICMLA 2012 link Value-based program characterization and its application to software plagiarism detection 2011 link CMCD: Count Matrix Based Code Clone Detection 2011 link Increme...
Understanding the structural determinants of a protein’s biochemical properties, such as activity and stability, is a major challenge in biology and medicine. Comparing computer simulations of protein variants with different biochemical properties is an
These ideas are implemented in diffTF to globally assess differential TF activity between two conditions (basic mode; Figure 1A; Figure S1A) and to classify TFs into activators and repressors (classification mode; Figure 1B). Basic mode is based on genome-wide accessibility or ChIP-seq (of ...
Cellular development and its associated biochemical processes within and between various cell types are determined by the relevant cellular proteomes, which are tightly regulated by biochemical synthesis, different stage genetic interactions and various metabolic pathways. The proteome of a cell is largely...