such as atrial fibrillation, diabetes, chronic obstructive pulmonary disease (COPD), and renal dysfunction. These comorbidities may be a cause, contributing factor for developing HFpEF, or an alternative diagnosis (“mimic”) for patients presenting with short...
Diastolic dysfunction of the left ventricle (LVDD) is equally common in elderly women and men. LVDD is a condition that can remain latent for a long time but is also held responsible for elevated left ventricular filling pressures and high pulmonary pressures that may result in (exercise-induced...
(60), 154 patients with HFpEF underwent a comprehensive CMR examination (stress/rest perfusion, cine function, and late gadolinium enhancement). Forty-two patients (27%) were found to have an alternative diagnosis consisted of coronary artery disease, microvascular dysfunction, hypertrophic ...
of diastolic dysfunction during exercise.9 This might suggest that diastolic stress test have high negative predictive value and could help to rule out HFpEF, but possibly could not distinguish different grade of LV diastolic dysfunction, which would be of a great importance in hypertensive patients....
women with HFpEF versus diabetic men with HFpEF; (2) regression analysis demonstrated that sex, DM and renal dysfunction are associated with plasma miR-34a levels in patients with LVDD; and (3) Increased levels of plasma Ang-2 in diabetic women with HFpEF but not in diabetic men with HFpEF...
Longitudinal data is needed to delineate the risk of transition from subclinical diastolic dysfunction in childhood to HFpEF later on in life. In conclusion, in a cross-sectional study among children, obesity was associated with increased LVM, LVH, increased LV filling pressures, and increased left...
Although diastolic dysfunction (DD), as a precursor of HFpEF, has been proposed as a pathological hallmark feature in this process,8 little is known regarding normative reference values of key diastolic parameters in Asians. Show abstract Recommendations for the Evaluation of Left Ventricular Diastolic...
Glycemic variabilityDiastolic functionEchocardiographyType 2 diabetes mellitus (T2DM) is a major cause of heart failure (HF) with preserved ejection fraction (HFpEF), usually presenting as left ventricular (LV) diastolic dysfunction. Thus, LV diastolic function should be considered a crucial marker of ...
Aims Left ventricular diastolic dysfunction (LVDD) is an early heart failure with preserved ejection fraction (HFpEF) phenotype that is reversible. Identifying dietary predictors associated with LVDD in diverse populations may help broadly improve HFpEF primary prevention. Methods and results This ...
Derangement of any of these components may produce the pathophysiological entity of diastolic dysfunction (Table 1), a leading cause of the important and growing clinical syndrome of heart failure with preserved ejection fraction (HFpEF), which now accounts for ≥50% of all heart failure cases (1...