,HemostasisandThrombosis:MethodsandProtocols,MethodsinMolecular Biology,vol.1646,DOI10.1007/978-1-4939-7196-1_21,©SpringerScience+BusinessMediaLLC2017 Chapter21 ChromogenicFactorVIIIAssaysforImprovedDiagnosis ofHemophiliaA SusanRodgersandElizabethDuncan Abstract HemophiliaAisaninheritedbleedingdisordercausedbya...
The treatments you need will depend on the type and severity of hemophilia. For instance, if you have mild hemophilia, you may need treatment only when you've been injured or in preparation for surgery. However, if you have severe hemophilia and bleed frequently, you may need regular treatmen...
In this case presentation we describe the diagnosis of hemophilia in a child presenting with postoperative bleeding from circumcision. We review the literature regarding the history of this disease with early surgery and highlight the current treatments....
hemophiliajoint diseaseMRIpower Doppler sonographysynovitisRecurrent hemarthroses in hemophilia results in synovitis and joint arthropathy. Primary prophylaxis when universally instituted at current doses can prevent joint deterioration but is expensive. Alternatively, the selective implementation of prophylaxis ...
1.A method for determining a subject's risk for developing hemophilia A, hemophilia B, or von Willebrand disease (VWD), the method comprising the steps of:(a) detecting a germline alteration in a group of genes associated with hemophilia A, hemophilia B or VWD, the group consisting of: hu...
On the nature and diagnosis of hemophilia: A. J. Quick. Blood 9: 265, September, 1954doi:10.1016/0030-4220(55)90283-8T.J.CElsevier Inc.Oral Surgery Oral Medicine Oral Pathology
For some families, carrier"s detection was done using this method. The results indicated that RFLP segregation analyses provide a useful method for carrier detection in hemophilia B.P GhandilDd FarhudS ZeinaliA GhadiriIranian Journal of Public Health...
Prenatal diagnosis of classic hemophilia (hemophilia A) in mid-trimester was achieved by means of immunoradiometric assays for factor VIII on fetal plasma and amniotic-fluid mixtures obtained by fetoscopy. Samples were analyzed from six male fetuses at risk for severe hemophilia and from nine contro...
Pediatric Research publishes original papers, invited reviews, and commentaries on the etiologies of diseases of children and disorders of development, extending from molecular biology to epidemiology. Use of model organisms and in vitro techniques relevant to developmental biology and medicine are ...
The primary cause of the defective hemostasis in hemophilia is the lack of thromboplastinogen in the blood. This anomaly is congenital and hereditary. The mechanism whereby the concentration of thromboplastinogen is depressed in the blood is not known and no satisfactory explanation can be given why...