Diagnosing eosinophilic asthma is important, because uncontrolled eosinophilic airway inflammation is associated with reduced response to glucocorticoids and increased risk of severe exacerbations.Currently, the diagnosis of eosinophilic asthma is based on measurements of sputum eosinophils, which is time consumi...
Diagnosis and management of eosinophilic asthma: a US perspective. J Asthma Allergy. 2014;7:53-65.Walford, H. H., Doherty, T. A. (2014) Diagnosis and management of eosinophilic asthma: a US perspective. J. Asthma Allergy 7, 53-65....
The presence of eosinophilic airway inflammation is supportive but not diagnostic of asthma. Until recently, this required induction of sputum to measure the eosinophil count; however, this procedure is associated with a risk of bronchospasm and requires specialist laboratory processing, which is rarely...
Asthma is a pathologically heterogeneous disease, and the phenotype is characterized by different types of airway inflammation. Exhaled nitric oxide (FENO) measurements are a surrogate marker specific for eosinophilic airway inflammation. The latter is usually associated with steroid responsiveness, and henc...
Despite the concept of eosinophilic sinusitis becoming accepted widely in recent years, the diagnostic criteria remain unclear and definitive diagnosis requires histological proof of eosinophilic infiltration. Since it is not feasible for private otolaryngologists to sample tissue from deep within the para...
Eosinophilic gastrointestinal disorder (EGID) was first described by Kaijer in 1937[18] and is characterized by infiltration of eosinophils into different layers of the gastrointestinal tract in the absence of secondary causes. EGID primarily involves eosinophilic esophagitis (EoE) and eosinophilic gastroen...
Symptoms of eosinophilic esophagitis include: Trouble swallowing solid foods, known asdysphagia Heartburn (reflux) or upperabdominal pain An itchy throat when you eat Food impaction, which is when food gets stuck in your esophagus (This may cause vomiting, or you might need a doctor to remove ...
Practical Considerations in Management of Non-eosinophilic Asthma Chapter© 2020 Keywords Asthma Differential diagnosis Pathophysiology 16.1Introduction 16.1.1History of Asthma The word asthma is derived from the Greek verb, aazein, which means to pant (Marketos 1982). Hippocrates was the first to use...
Diagnosis and management of eosinophilic asthma: a US perspective Eosinophilic asthma is now recognized as an important subphenotype of asthma based on the pattern of inflammatory cellular infiltrate in the airway. Eosino... HH Walford,TA Doherty - 《Journal of Asthma & Allergy》 被引量: 73发表...
Features of eosinophilic esophagitis (EoE) and gastroesophageal reflux disease (GERD) overlap; because they cannot be differentiated on the basis of eosinophil counts alone, it can be a challenge to distinguish these disorders. We aimed to characterize the clinical, endoscopic, and histologic features...