Patients present with manifestations of hypoglycemia and metabolic acidosis typically around 3 to 4 months of age. In patients suspected of having the disease, genetic testing is the investigation of choice to confirm the diagnosis. Dietary treatment prevents hypoglycemia and improves the life expectancy...
Prevalence of metformin use and the associated risk of metabolic acidosis in US diabetic adults with CKD: a national cross-sectional study. Medicine (Baltimore). 2015;94(51):e2175.PubMedGoogle ScholarCrossref 29. Richy FF, Sabidó-Espin M, Guedes S, Corvino FA, Gottwald-Hostalek U. ...
Beyond the metabolic point of view, a patient with COVID-19 infection and T2DM has a poorer prognosis and is more likely to develop severe forms of COVID-19 infection and die from them [4]. AIM OF THE STUDY This systematic review aimed to identify/estab- lish the possible connection ...
A smaller number of patients (4500) were discharged after treatment for diabetic coma (ICD-9-CM 250.3), 10,800 for hyperosmolar coma (ICD-9-CM 250.2), and 18,800 for acidosis (ICD-9-CM 276.2). 16 Decompensated diabetes imposes a heavy burden in terms of economics and patient outcomes...
It is defined by hyperglycemia, metabolic acidosis, and the production of ketoacids, and hyperglycemia leads to an osmotic diuresis that causes volume depletion. It may occur at the initial presentation of newly diagnosed type 1 diabetes, or in a child with preexisting type 1 diabetes in times...
Two large observational studies, however, demonstrated that metformin significantly reduced the risk of death and hospitalization compared to sulfonylurea monotherapy in patients with HF, without causing additional metabolic acidosis. In response to these results, FDA removed the warning for HF patients in...
The role of metformin (MET) in the treatment of patients with advanced HFrEF and type 2 diabetes mellitus (DM) is not firmly established. We studied the impact of MET on metabolic profile, quality of life (QoL) and survival in these patients. A total of 847 stable patients with advanced ...
The term "ketosis-prone type 2 diabetes (T2DM)" is often used to describe the A-β+ patients who present with new onset diabetes, unprovoked diabetic ketoacidosis (DKA)8,9 and acidosis10–12. As a result, the prevalence of ketosis-prone T2DM could be grossly underestimated. In ...
(1.22–1.85), respectively. The cumulative incidences of asthma development, exacerbation, and hospitalization for asthma were significantly higher in metformin users than nonusers (p< 0.001). A longer cumulative duration of metformin use for more than 728 days was associated with significantly higher...
Orthorexia nervosa (ON) is an unspecified feeding or eating disorder (USFED) characterized by an exaggerated, unhealthy obsession with healthy eating. Τypical eating disorders (EDs) and USFEDs are common among patients with diabetes mellitus (DM), which complicates metabolic control and disease ou...