The role of mitochondria in insulin resistance and type 2 diabetes mellitus. Nat Rev Endocrinol. 2012; 8 (2):92–103. doi: 10.1038/nrendo.2011.138. [ Cross Ref ]Szendroedi J, Phielix E, Roden M (2012) The role of mitochondria in insulin resistance and type 2 diabetes mellitus. Nat ...
Type 2 diabetes mellitus, the most frequent subtype of diabetes, is a disease characterized by high levels of blood glucose (hyperglycaemia). It arises from a resistance to and relative deficiency of the pancreatic β-cell hormone insulin. ...
your pancreas makes someinsulin— the hormone that helps your cells turn glucose (a type of sugar) from the food you eat into energy. In some people, your cells don't respond to this hormone as they should (a condition called insulin resistance). ...
If you want to reverse your type 2 diabetes and insulin resistance, you will have to exercise regularly. Exercises very critical for the improvement of insulin sensitivity. It is beneficial for you because it can reduce body fat, and improve sugar metabolism. If you exercise regularly, it will...
Type 2 diabetes is a condition in which the cells cannot use blood sugar efficiently to meet the body’s needs. Learn about symptoms, causes, vs. type 1 diabetes, diet, exercise, treatment, insulin, medications, life expectancy, and other lifestyle chang
This contributes to the pathogenesis of several diseases, including obesity-related insulin resistance (IR) and type 2 diabetes (T2D) [1]. This is typically manifest by an excess of nutrients which cause adipose tissue (AT) and pancreatic β-cells to secrete cytokines, thereby making them the ...
Insulin resistance is a core feature of type 2 diabetes mellitus (T2DM) and contributes not only to the hyperglycaemia that defines diabetes mellitus but also to the hyperlipidaemia, inflammation, oxidative stress and atherosclerosis that accompany it ...
Evolutionary pressures, such as acute infections at the population level (pandemics) and chronic low exposure to environmental products or infectious agents, may have contributed to increased susceptibility and to the current increase in the prevalence of insulin resistance and type 2 diabetes. Then: ...
Insulin resistance is a core feature of type 2 diabetes mellitus (T2DM) and contributes not only to the hyperglycaemia that defines diabetes mellitus but also to the hyperlipidaemia, inflammation, oxidative stress and atherosclerosis that accompany it T2DM substantially increases risk of not only cerebro...
Obesity is associated with an increased risk of developing insulin resistance and type 2 diabetes. In obese individuals, adipose tissue releases increased amounts of non-esterified fatty acids, glycerol, hormones, pro-inflammatory cytokines and other factors that are involved in the development of insu...