Pathophysiology of type 1 and type 2 diabetes mellitus: a 90-year perspective. Postgrad Med J. 2016;92(1084):63-9.F. Zaccardi, D. R. Webb, T. Yates, and M. J. Davies, "Patho- physiology of type 1 and type 2 diabetes mellitus: a 90-year perspective," Postgraduate Medical ...
This chapter reviews the etiopathogenesis of type 1 diabetes, which includes genetic (such as a strong association with HLA haplotypes, genetic linkage with immune system genes), immunological (such as specificity for beta cells and the presence of antigen-specific T cells), environmental factors (s...
Type 2 was called adult onset, type 1 was juvenile onset, and it was just an age thing. It’s 2 different diseases.Helena W. Rodbard, MD: It is totally different. And in fact, a lot of people with type 2 diabetes I think [are] misdiagnosed and vice versa. People with type 1 di...
Apoptosis plays an important role in the pathophysiology of both type 1 and type 2 diabetes. In type 1 diabetes, β-cell death by apoptosis following autoimmune insulitis causes an absolute insulin deficiency triggered by an extrinsic receptor-mediated pathway, which activates a cascade of caspase ...
Type 1 and type 2 diabetes are characterized by chronic inflammation; both diseases involve pancreatic islet inflammation, while systemic low-grade inflammation is a feature of obesity and type 2 diabetes. Long-term activation of the innate immune system impairs insulin secretion and action, and infl...
Pathophysiology of type 1 and type 2 diabetes mellitus: a 90-year perspective Diabetes mellitus is a complex metabolic disorder associated with an increased risk of microvascular and macrovascular disease; its main clinical character... Francesco,Zaccardi,David,... - 《Postgraduate Medical Journal》 ...
Scheen AJ (2003) Pathophysiology of type 2 diabetes. Acta Clin Belg 58: 335-341.Scheen AJ. Pathophysiology of type 2 diabetes. Acta Clinica Belgica. 2003;58(6):335-341.Dagogo-Jack S, Santiago JV (1997). Pathophysiology of type 2 diabetes :...
Pathophysiology, Etiology, Epidemiology of Type 1 Diabetes and Computational Approaches for Immune Targets and Therapy. Autoimmune diseases occur when the body's natural defense system fails to differentiate its own cells from the foreign cells and mistakenly attacks the hea... Begum,Dariya,Gayathri,....
et al. SARS-CoV-2 infections and presymptomatic type 1 diabetes autoimmunity in children and adolescents from Colorado, USA, and Bavaria, Germany. JAMA 328, 1252–1255 (2022). Article CAS PubMed PubMed Central Google Scholar Del Chierico, F. et al. Pathophysiology of type 1 diabetes and ...
Pathophysiology of type 1 and type 2 diabetes mellitus: a 90-year perspective Diabetes mellitus is a complex metabolic disorder associated with an increased risk of microvascular and macrovascular disease; its main clinical character... F Zaccardi,DR Webb,T Yates,... - 《Postgraduate Medical Journ...