Innate lymphoid cells (ILCs) are critical to effective immune surveillance against pathogens, have malignant counterparts, and contribute to disease. Thus, it is important to understand ILC development. All ILCs are derived from the common lymphoid progenitor cell; however, the exact mechanisms and ...
Spatial-temporal distribution and tissue-specific transcriptional heterogeneity of ILCs at single-cell resolution in adult human tissues have been revealed in recent years while those in human fetal tissues remain poorly characterized.42,43,44,45Thymus, the primary lymphoid tissue for T cell production,...
Innate lymphoid cells (ILCs) are a family of immune effector cells that have important roles in host defense, metabolic homeostasis and tissue repair but can also contribute to inflammatory diseases such as asthma and colitis. These cells can be categorized into three groups on the basis of the...
Signatures of Human NK Cell Development and Terminal Differentiation Natural killer (NK) cells are part of the innate lymphoid cell (ILC) family and represent the main cytotoxic population. NK cells develop from bone marrow ... M Luetke-Eversloh,M Killig,C Romagnani - 《Frontiers in Immunology...
The innate lymphoid cell (ILC) family has recently expanded with the discovery of type-2 innate lymphoid cells (ILC2). These cells arise from lymphoid prog... JA Walker,AN Mckenzie - 《Current Opinion in Immunology》 被引量: 140发表: 2013年 Human natural killer cell development in secondary...
et al. Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus. Nat. Immunol. 12, 1045–1054 (2011). CAS PubMed PubMed Central Google Scholar Klose, C.S. et al. Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid ...
We have studied the human appendix vermiformis (AV), a GALT organ, to obtain information on (1) the postnatal development of the lymphoid tissue and the time of appearance of plasma cells containing immunoglobulins (Ig); (2) the distribution of the Ig classes in mucosal plasma cells versus ...
Induction of bronchus-associated lymphoid tissue is an early life adaptation for promoting human B cell immunity Article 17 July 2023 Structural cells are key regulators of organ-specific immune responses Article 01 July 2020 References Eikelenboom, P., Nassy, J.J., Post, J., Versteeg, ...
Objective To investigate the histogenesis of lymphoid tissue and the development of T and B lymphocytes in human fetal appendix.Methods Totally 26 samples of human fetal appendix from the fetus at the 9th to 28th gestational week were collected with informed consent signed by the fetus' parents.Th...
We have identified conditions for forming cultured human umbillical vein endothelial cells (HUVEC) into tubes within a three-dimensional gel that on implan... JS Schechner,AK Nath,L Zheng,... - 《Proceedings of the National Academy of Sciences of the United States of America》 被引量: 790...