Dengue is caused by infection with any one of four related dengue virus (DENV) serotypes that belongs to the genus Flavivirus. Although most dengue infections are asymptomatic, patients can present with a wide spec- trum of clinical symptoms ranging from mild febrile illness through to severe ...
Dengue viruses (DENV) are positive-stranded RNA viruses belonging to the Flaviviridae family. DENV is the causative agent of dengue, the most rapidly spreading viral disease transmitted by mosquitoes. Each year, millions of people contract the virus through bites from infected female mosquitoes of th...
Dengue viruses (DENV) are positive-stranded RNA viruses belonging to the Flaviviridae family. DENV is the causative agent of dengue, the most rapidly spreading viral disease transmitted by mosquitoes. Each year, millions of people contract the virus through bites from infected female mosquitoes of th...
Dengue fever (DF) is an arthropod-borne viral infection caused by the dengue virus (DENV) that belongs to the Flaviviridae family and consists of four phylogenetically and antigenically distinct serotypes (DENV 1–4) transmitted by the bites of Aedes [1]. An infection from the virus may be ...
dengue virusdrug discoveryflavivirusinhibitorDengue fever is caused by infections with dengue virus, the most prevalent mosquito-borne viral pathogen in humans. There are no drugs available to treat dengue virus infection. Here, we discuss the strategies and challenges to develop dengue drugs. ...
First, it was triggered by an imported case which was misdiagnosed. Dengue is not a major infectious disease in China. Some of the doctors in Xintang community, where this dengue outbreak occurred, were from North of China where there is a lack of experience in dengue diagnosis and therapy....
Dengue is one of the most important mosquito-borne viral infections caused by single-stranded RNA virus that are transmitted by the Aedes aegypti and Aedes albopictus mosquito species. Dengue is endemic in over 140 countries in Asia, the USA, the Eastern
The DENV-1 strain isolated during the 2006 epidemic is closely related to the strains isolated during the 2001 epidemic (Figure 1B). It suggested that DENV probably circulated in local and caused the epidemics of 2001 and 2006. Moreover, there were several clear divisions within the Chinese ...
The Pathogen and Disease Dengue virus is classified as a species in the family Flaviviridae, which includes other pathogens, such as yellow fever virus. Four serotypes of dengue virus are recognized and referenced numerically (often as DEN-1 through DEN-4). The prevalence of the four serotypes...
to kill but nonetheless release inflam- matory cytokines that contribute to disease severity51; that severe disease is caused by DENVs of increased virulence52; and the suggestion that cross-reactivity between NS1 and human platelets and endothelial cells raises antibodies that damage these cells53....