PI3Kγ−/− mice are protected from severe dengue disease caused by an adapted DENV-3 strain To investigate the role of the PI3Kγ pathway in a mouse model of severe dengue disease, mice lacking PI3Kγ, and t
105As the mechanism of action is complex and involves more than one protein, the potential for resistance selection is greatly reduced.B. thuringiensisvar.israelensisis available in numerous formulations, which can be applied by hand or as a spray,98thus allowing the microorganism to be used in ...
Knockdown resistance (kdr, also known as theVsscmutation) is the major mechanism of sodium channel insensitivity to both DDT and pyrethroids [57,58]. MostVsscmutations are located at domains IS6, IIS6 and IIIS6.kdrcaused by point mutations of the target site, with the substitution of leucine...
Dengue may be caused by one of the serotypes DEN-1 to DEN-4. For the most part, septicity with one serotype presents upcoming defensive resistance against that specific serotype yet not against different serotypes. When anyone is infected for the second time with various serotypes, a serious...
Dengue fever (DF)/dengue hemorrhagic fever (DHF) is caused by infection with dengue viruses. There are four closely related virus serotypes i.e, D1, D2, D3, and D4. Extensive cross-reactivity among the different dengue serotypes is shown... J Rabablert 被引量: 0发表: 2005年 加载...
and to guide for the use of repellent and appropriate clothes on a personal level. However, these measures are not sufficient in view of cost and effect. Therefore, prevention of infection or prevention of incidence by a vaccine is desired which can be inoculated in a wide age range and exh...
Dengue fever (DF) is one of the most common vector-borne diseases in the world, mostly found in tropical as well as in subtropical regions. Dengue virus (DENV), the causative microorganism of DF and dengue hemorrhagic fever (DHF), is a member of the Flavivirus genus and belongs to the ...