Kulakova N, Urban B, McMichael AJ, Ho LP. Functional analysis of dendritic cell-T cell interaction in sarcoidosis. Clin Exp Immunol: 159(1): 82-86.Kulakova N,Urban B,McMichael A. Functional analysis of dendritic cell-T cell interaction in sarcoidosis.[J].Clinical and Experimental Immunology...
Cancer-associated fibroblast-targeted strategy enhances antitumor immune responses in dendritic cell-based vaccine. Given the close interaction between tumor cells and stromal cells in the tumor microenvironment (TME), TME-targeted strategies would be promising for devel... Y Ohshio,K Teramoto,J Hanaok...
the Tht program is primed in tumor-draining lymph nodes by dendritic cells presenting tumor antigens, and that their function is important for harnessing the antitumor response of anti-PD-1 treatment. Our molecular and functional findings support the modulation of Tht–dendritic cell interaction check...
Immunology & Cell BiologyDemangel, C., Britton, W. J. (2000). Interaction of dendritic cells with mycobacteria: where the action starts. Immunol. Cell Biol. 78:318-324.Demangel, C., and W.J. Britton. 2000. Interaction of den- dritic cells with mycobacteria: where the action starts. ...
Here, we review the requirements for T cells and dendritic cells (DCs) to enter initial afferent lymph vessels of the skin. We discuss how these cells subsequently gain access to the paracortex of draining lymph nodes; a location that allows for efficient interaction between both cell ...
However, treatment with any of the inhibitors alone or in combination did not change the avidity of CD8+ T cells in peptide titration assays with T2.A1 cells. T-helper cell/DC interaction is a bi-directional process that normally results in DC activation. Vemurafenib and vemurafenib/cobimetinib...
The overall avidity of the interaction influences the probability that T cells will be stably captured by DCs, providing a possible basis for T cell competition. Taken together, our results identify the cellular behaviors that promote an efficient CD8+ T cell response in the lymph node. This is...
作者: CM Celluzzi,FL Jr 摘要: Dendritic cells (DCs) are potent professional APCs capable of presenting Ag in the context of costimulatory signals necessary for T cell activation. Although tumor cells express target Ags, they are generally incapable of stimulating an immune response. We show that...
Here, we investigated the clinical significance of circulating pDCs and their interaction with tumor-specific T cell responses in patients with non-small cell lung cancer (NSCLC,n=126) . The relation between intratumoral pDC signature and immune checkpoint inhibitors efficacy was also evaluated. ...
Effector T cell responses can be modulated by competing positive or negative signals transduced by natural killer (NK) cell receptors. This raises the poss... Groh,Veronika,Brühl,... - 《Proceedings of the National Academy of Sciences of the United States of America》 被引量: 660发表: 2003...