In infrared(IR)-MALDESI, exogenous water in the form of ice can be used as a matrix to improve the desorption of neutrals by matching the excitation laser wavelength with the O-H stretching modes (2.94 microm). IR-MALDESI is also an ambient pressure ionization source, meaning that ions ...
CIS is a method for improving the ionization efficiency of non-polar compounds by adding metal ions to the electrospray solvent. alpha-Tocopherol and an ether-linked analogue known as alpha-TEA were analyzed in concentrations from 1.25--40 mug/mL (1.9--60 pg consumed). The response curve was...