Just as average expression of PAM50 genes in tumor cells from snRNA-seq could discriminate tumor subtype, chromatin accessibility in the promoters of PAM50 genes from snATAC-seq showed good segregation of tumors by subtype in the 21 samples (from 21 cases) with both data types available (Fig....
What determines the maximum magnifications one can have in an optical microscope? Define ampere. Define magnification in astronomy. What is mean by an eyepiece? What do you understand by the term magnification? What is meant by a power diagram? Explain the difference between "real" and "virtual...
To quantify the amount of tumor in each bladder specimen, the H&E-stained slides were scanned at low magnification and digitized using the TissueFAXS system (TissueGnostics, Los Angeles, CA, USA). The acquired images were analyzed using TissueGnostics’ HistoQuest cell analysis software. Prior to ...
FISH slides were examined with an AxioImager Z1 microscope (Carl Zeiss Microscopy, New York, USA) using the ISIS software from MetaSystems (Altlussheim, Germany). Signals were counted with x63 magnification in at least 200 non-overlapping tumor cell nuclei in each section. A signal ratio of...
Staining was observed in putative stem cell niches at the bottom of EACs (arrows) (e). Original magnification × 200. Gene expression of LgR5 in human BE and EAC (x-fold difference mRNA). LgR5 gene expression in BE-associated EAC (1) was significantly (p = 0.0159) higher in ...
To quantify the extent of coincidence between MBP (myelinated) and Gal-4-containing axon segments, Gal-4 and MBP fluorescence intensities were measured along single axons in microscope images of neuron/OLG co-cultures. Clearly visible axon portions were selected, and ROIs were created by tracing...
Inserts show high magnifications of the boxed areas. White arrows indicate co-localization. Scale bar, 10 µm. c Co-localization between injected early endosomes and endogenous markers (in % of all labeled injected endosomes). In this and all subsequent figures, the data show mean values...
This archaeometric study aims at characterizing the archaeological finds belonging to the lithic industry from La Calvera rock shelter (Camaleño, Cantabria) and at hypothesizing the possible provenance of each material. The site, located in the mountainous area of Picos de Europa National Park ...