Exponential decay curves were fitted for the risk by the age of 20 years. Results The risk of islet autoantibodies by the age of 20 years was 8%, 4.6%, 2.6% and 0.9%, at the landmark ages of birth, 3.5, 6.5 and 12.5 years, respectively. The short-term risks (within 6...
The restricted cubic spline transformation decomposes EYO into one linear term and one cubic term, which ensures the resulting fitted curve is smooth and continuous at each quantile segment. We used a Bayesian framework to analyze the relationship between biomarkers and the independent variables and ...
Long-term followup of breast cancer patients: The 30-year report A cohort of 1458 breast cancer patients treated by radical mastectomy in the years 1940–1943 has been followed since that time. There are 184 known alive ... Frank,Adair,MD,... - 《Cancer》 被引量: 1893发表: 1974年 Pre...
We determined somatic and germline variants in the cohort (Fig.1eand Supplementary Tables2and3) using WES. Consistent with previous studies, we detected several cases with somatic mutations inTP53andPIK3CA(Fig.1e). For germline variants, we identified two potential pathogenic germline variants inBRC...
If the need for reinvention is such a standard aspect of the contemporary world, why are we having so much trouble still trying to carry it out? Many are disowning the traditional pathways to success and building an entirely new model for professional work. It spans all age groups, industr...
That is, researchers define flourishing in terms of the presence of wellbeing, and languishing in terms of the absence wellbeing. There may be significant limitations for current flourishing frameworks where existing flourishing definitions are based on wellbeing (note, the term positive mental health...
Exponential decay curves were fitted for the risk by the age of 20years.The risk of islet autoantibodies by the age of 20years was 8%, 4.6%, 2.6% and 0.9%, at the landmark ages of birth, 3.5, 6.5 and 12.5years, respectively. The short-term risks (within 6years of follow-up) at...
Make the Definition Evaluative The idea of a "problem" usually means that people think there is something wrong with the world, but wrong is a debatable term. Even if everyone accepts the same facts, not everyone will agree that the facts you (or others) have defined as a prob- lem ...
Prostate adenocarcinoma (PRAD) persists as the predominant non-cutaneous malignancy diagnosed in males, which is a primary contributor to cancer-related mortality globally. It is reported that the progression of prostate adenocarcinoma is associated with
lines displaying abnormal karyotypes or genomic rearrangements >1 Mb were excluded from our study. The final cohort used in this work included 297 distinct donors of which 153 were male and 144 were female, with an average age of 21 ± 10 (sd) years. Of the 297 donors, 207 had ...