While normative movement behaviour is frequently used to characterise population behaviour, we demonstrate the value of leveraging heterogeneity in the behaviour to gain greater insight into population structure and the mechanisms driving space‐use tactics.doi:10.1111/ele.13327Guillaume Bastille-RousseauGeorge WittemyerJohn Wiley & Sons, Ltd (10....
2a). gRNAs with a high off-target score were excluded from further analysis (1.2% of gRNAs; Extended Data Fig. 2b; Methods). Fig. 1: Base editing screens map functional domains in oncogenes. a, Overview of base editing screens to identify drug resistance variants in cancer cell models. ...
Namespace:matlab Define entity type expand all in page Syntax entitytype=entityType(name) entitytype=entityType(name,datatype) entitytype=entityType(name,datatype,dimensions) entitytype=entityType(name,datatype,dimensions,complexity) Description ...
The order key allows an app author to specify the order in which the controls are displayed to the user. In order to insert a blank, no control, at a specific location use the ph data_type with the order key. For example, to display a blank space between the first and second control...
10. For example, complexity in RNA splicing is a main characteristic of tumor heterogeneity related to metastasis, drug sensitivity, and relapse, thereby serving as a prognostic marker for multiple cancer types, including breast cancer11, glioblastoma12, non-small cell lung cancer13, and ovarian ...
DNA was extracted from cell pellets (Qiagen) and the gRNA cassette was PCR amplified (PCR1, 28 cycles, 3 µg per reaction) with several reactions in parallel to maintain the complexity of the library. After column purification of PCR1 products (Qiagen), PCR products were indexed by PCR...
This review provides an overview of the basic principles of cell types rooted in evolution and development and discusses approaches to characterize and classify cell types and investigate how they contribute to the organism’s function, using the mammalian brain as a primary example. I propose a ...
In order for an application running in the User space to run a privileged instruction (in the kernel space), it initiates a system call to the operating system's API. There are many different types of system calls. Answer and Explanation:1 ...
These yolk globules themselves are not directly responsible for the fluoxetine-resistant phenotype of these animals because males of these genotypes lack yolk and are also Nrf (data not shown). In C. elegans, yolk proteins are synthesized in the intestine, secreted into the pseudocoelomic space, ...
Missense driver mutations in cancer are concentrated in a few hotspots1. Various mechanisms have been proposed to explain this skew, including biased mutational processes2, phenotypic differences3–6 and immunoediting of neoantigens7,8; however, to our k