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essential amino acids and essential fatty acids, as well as all vitamins and minerals from the group of micronutrients, must be consumed in appropriate quantities A diet high in processed and refined foods can lead to excessive intake as well as deficiencies of certain nutrients Non-essential ...
by exchanging the corresponding regions between Nlalpha1 and Nlalpha3 to generate different chimeras, amino acid residues or residue clusters in the regions outside the six loops were found to play essential roles in agonist binding, especially for the amino acid clusters between loop B and C. ...
As controls, we included nontargeting gRNAs (NT gRNAs) (n = 57), intergenic-targeting gRNAs (n = 168) and gRNAs predicted to introduce splice variants21 in nonessential (n = 87) and essential (n = 316) genes22,23 (Supplementary Table 1). To maximize the saturation...
INTRODUCTIONSialic acids are essential components of glycoconjugates on deuterostomia cells [1]. They have been shown to be involved in many biological pro... A Blume,W Weidemann,U Stelzl†,... 被引量: 0发表: 0年 加载更多来源期刊 American Journal of Human Genetics 1999 Jun; 研究点推荐...
The four minor pilins are essential for secretion In our quest to understand the structure-function relationship of the minor pseudopilin complex, we assessed the independent requirement of each of the four minor pseudopilins of the P. aeruginosa Xcp T2SS during the secretion process. In-frame...
Thus, ionic charge interaction at this position is probably not an essential factor in determining the GFP structure and function. Since Ile is a hydrophobic amino acid, it is possible that the hydrophobic character of the amino acid may be important to GFP structure and function. To determine ...
Brn3 is Essential for Terminal Osteoclast Differentiation and Bone Resorptive Activity The functional effect of Brn3 transcription factors on osteoclast differentiation was investigated by transfecting decoy oligonucleotides into cells, which causes a suppression of Brn3 DNA binding activity. Functional inhi...
DIABETIC CAPD PATIENTSKyu-Hyang Cho, Jun-Young Do, Soek-Hui Kang, Jong-Won Park, Kyung-Woo YoonDepartment of Internal Medicine, Yeungnam University Hospital, Daegu, Korea.Purpose: Preservation of residual renal function (RRF) in peritonealdialysis patient is essential to improve clinical outcomes. ...
S. Essential role for the CRAC activation domain in store-dependent oligomerization of STIM1. Mol. Biol. Cell 21, 1897–1907 (2010). 16. Hou, X., Pedi, L., Diver, M. M. & Long, S. B. Crystal structure of the calcium release-activated calcium channel Orai. Science 338, 1308–...