S8). Thus, Scriabin revealed the concomitant use of opposing signaling modalities between CD14 monocytes and CD8 TEM cells in response to highly pathogenic Lentivirus infection, underscoring the utility of using single-cell resolution CCC methods to capture the full structure of CCC phenotypes. Broad ...
Concomitant analyses of six biomarkers, including FAP, CD29 (integrin-β1), α-SMA, FSP1, PDGFRβ, and caveolin, characterized four CAF subsets (from CAF-S1 to CAF-S4) with distinct properties in ovarian and breast cancers (BC) [94,98]. Kieffer et al. further identified eight different ...
The repression of E-cadherin transcription by the EMT inducers Snail1 and Zeb2 plays a fundamental role in defining embryonic territories in the mouse, as E-cadherin needs to be downregulated in the primitive streak and in the epiblast, concomitant with the formation of mesendodermal precursors ...
In summary, exclusion criteria for concomitant valve disease varied slightly in pivotal trials with NOACs for stroke prevention in AF, with exclusion of most valvular disease patients implemented in some studies, while others included some patients with non-rheumatic valvular disease, valve repair or ...
It appears that on occasion data management would create Concomitant Medication CRFs with almost any and all units that could ever be possible for medications. Sometimes this list can be on the order of 60-75 units. Would you still advocate that the codelist contain all 75 potential values?
However, the same mutant bound fibrinogen in the presence of Mn2+, when activated by monoclonal antibody PT25-2 or by forcing the integrin legs to extend by concomitant αIIbQ595NTT mutation. We engineered another mutation that was designed specifically to prevent the swing-out. Likewise, this...
Buprenorphine-induced antinociception is mediated by mu-opioid receptors and compromised by concomitant activation of opioid receptor-like receptors. Buprenorphine is a mixed opioid receptor agonist-antagonist used clinically for maintenance therapy in opiate addicts and pain management. Dose-response cu......
(Eucalyptus globulus Labill. and Pinus radiata D. Don) with contrasting drought response strategies were performed to (i) assess changes in radial stem growth, transpiration, leaf water potential and gas exchange in response to chronic drought, and (ii) evaluate the concomitant impacts of these ...
By contrast, only one of the three patients with R175H-mutant tumours had neopeptide reactivity; this patient (07E) had one of the largest expansions for the mutant TP53 allele and a concomitant increase in protein abundance as well as a positive response to anti-PD-L1 treatment (Fig. 3a...
The percent of placebo-corrected changes from baseline for LDL-C (estimated by Friedewald calculation [Fc-LDL-C]) and HDL-C after 24 weeks of anacetrapib 100 mg/day were compared among patients by age, gender, race, diabetes status, type of concomitant statin with or without other lipid the...