229 kidney cells. Heritability analysis reveals that methylation variation explains a larger fraction of heritability than gene expression. We present a multi-stage prioritization strategy and prioritize target genes for 87% of kidney function loci. We highlight key roles of proximal tubules and ...
We first performed feature selection to select the top disease biomarkers. Instead of using a simple one-shot feature selection technique that usually yields a sub-optimal solution, we used a two-step feature selection process that generates better performance: backward feature elimination followed by ...
We first performed feature selection to select the top disease biomarkers. Instead of using a simple one-shot feature selection technique that usually yields a sub-optimal solution, we used a two-step feature selection process that generates better performance: backward feature elimination followed by ...
Our study hints to a unique stage in viral life cycle, which is not yet being understood completely. PCR-based DNA studies would not identify this stage in viral life cycle as a clinically important stage in virus activation. However, molecular impact of this stage of HHV-6 on host cell s...