A global commission of experts has called for a radical shift in how obesity is diagnosed, with less reliance on body mass index (BMI) to define disease. The commission, published in Lancet Diabetes and Endocrinology and endorsed by over 75 medical organisations across the world,1 said ...
近的文獻顯示,當控制在固定的身體質指(BMI)時,亞洲人的代謝徵候群風險比白種人高,因此一般認為要以較低的BMI點定義亞洲人的過重與肥胖才好.然而,對於亞洲地區的同族群而言,即使控制在固定的身體質指值之下,身體脂肪含和代謝反應仍然有些差距.因此,專家建議從多個大致上間隔相當的「動點」(包括23,25,27.5,30和...
Methods: Assessments of body composition, using a four-component model, and biochemical indices were obtained in 19 patients [mean (SD): age, 60 (8.3) years; BMI, 25.3 (3.3) kg/m2] with poorly controlled type 2 dia- betes, despite maximal oral hypoglycaemic agents, re- ceiving insulin ...
Mouse monoclonal SOX10 Biocare Medical Cat# ACI3099C Rabbit monoclonal PD-L1 (E1L3N) Cell Signaling Technology Cat# 13684, RRID: AB_2687655 Rabbit monoclonal CD8 (SP16) Sigma-Aldrich Cat# SAB5500074 Mouse monoclonal EOMES (WD1928) Thermo Fisher Scientific Cat# 14-4877-82; RRID: AB_2572882...
Six healthy premenopausal, weight-stable females aged 20–40 years with a body mass index (BMI) (calculated as weight in kilograms divided by height in meters squared) between 27 and 40 kg/m2 were recruited in Orlando using advertisements approved by an institutional review board. Subjects wer...
People in the obese group,with a BMI higher than 35and who continued to gain weight,faced the worst among all the groups in the study.But next-to-last were normal-weight people who lost weight,but this was likely because they became sick,the researchers said....
MMR status was the strongest predictor of microbial community variance in comparison to sample location (proximal/distal and on/off tumor), body mass index (BMI), age, and sex. Separate analyses of the dMMR and pMMR microbial communities revealed that many common CRC-associated microbial ...
To determine the composition of the various PRC1 complexes in human cells, we performed tandem affinity purification (TAP) from 293TREx cells stably expressing doxycycline-inducible NSPC1/PCGF1, MEL18/PCGF2, PCGF3, BMI1/PCGF4, PCGF5, MBLR/PCGF6, or RING1B, each fused with sequential N-...
62 new coding loci were added to the reference genome annotation. These genomes identified a large, previously unannotated, gene (Efcab3-like) encoding 5,874 amino acids. MutantEfcab3-likemice display anomalies in multiple brain regions, suggesting a possible role for this gene in the regulation...
12 The FGF-2-induced KDM2B, in concert with pre-existing EZH2, represses the expression of these microRNAs, leading to the upregulation of BMI1, EZH2, SUZ12 and RING1B and the functional activation of the polycomb complexes PRC1 and PRC2. One of the microRNAs targeted by this pathway ...