Gene products of the human HLA region are the principal histocompatibility barrier to human allogeneic tissue transplantation 1 . In addition, HLA genes regulate immune responses to environmental antigens 2 and affect susceptibility to various diseases 3 . Although the HLA region has been studied inten...
Belayer: Modeling discrete and continuous spatial variation in gene expression from spatially resolved transcriptomics Spatially resolved transcriptomics (SRT) technologies measure gene expression at known locations in a tissue slice, enabling the identification of spatiall... C Ma,U Chitra,S Zhang,......
Stromal cells maintain immune cell homeostasis in adipose tissue via production of interleukin-33 Sci Immunol, 4 (2019) Google Scholar Recent report showing that adipose tissue stromal cells produce IL-33. 27• M.W. Dahlgren, S.W. Jones, K.M. Cautivo, A. Dubinin, J.F. Ortiz-Carpena,...
Thus, rather than relying on a single focus of modification, sex differences in motor dynamics require independent modifications to multiple tissue types. Our results suggest shared motor behaviors may be sex-specifically optimized though distributed modifications to several aspects of morphology and ...
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Intestinal stromal cells are known to modulate the propagation and differentiation of intestinal stem cells1,2. However, the precise cellular and molecular mechanisms by which this diverse stromal cell population maintains tissue homeostasis and repair a
Significant differences in cell-type abundance were identified with both Wilcoxon testing and a generalized linear model-based method called Milo16, which produced consistent results. For example, regulatory T cells (Tregs) were enriched in polyps relative to unaffected tissue, while naive B, memory ...
Without signs of Alzheimer's disease, the researchers looked at the involvement of one possible culprit—a buildup of a protein called TDP-43 in thelimbic systemthat scientists have found in the autopsiedbrain tissueofolder adults. Researchers have classified the build-up of these protein deposits...
Include the types of proteins involved, the fluctuations in their abundance, and their functions. How does DNA describe the shape and function of organelles, cells, tissue, organs, and systems? Briefly describe two cell cycle checkpoints and why they are important in t...
In recent years, gene inactivation in the mouse and other model systems has shed new light on the processes of inductive tissue interactions and morphogene... Maxime,Bouchard - 《Differentiation》 被引量: 119发表: 2004年 Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and ...