53. Conservation Biology24m Conservation Biology 24m 38. Animal Form and Function Topic summary 1 concept Animal Physiology and Fitness Trade-Offs Video duration: 10m AI tutor 1 30 2 concept Tissues and Organs AI tutor 0 19 3 concept
Here, we present an easy-to-implement imaging mass cytometry workflow that ranges from antibody selection and testing to running a full panel. Additionally, we discuss the standard steps of IMC analysis and the currently available tools. Overall, the protocols proposed here are directly applicable ...
The workflow can be combined with antibody staining, for instance, to target extracellular factors such as matrix proteins and cell-cell communication molecules to enhance the definition of cell-cell interactions in pathological niches79. The thickness of tissue sections could be increased for higher ...
Single-molecule localization microscopy is a powerful tool for visualizing subcellular structures, interactions and protein functions in biological research. However, inhomogeneous refractive indices inside cells and tissues distort the fluorescent signa
However, one cannot attribute biological meaning to these observations, since the method of normalization by definition fixes each sample to have the same “total abundance”, which then gets shared out among all proteins. The normalized protein abundance distribution in data sets indicated a lower ...
Learn more about this topic: Diffusion | Overview & Definition from Chapter 4 / Lesson 15 42K In this lesson, learn what is the definition of diffusion and find a detailed explanation to learn what is diffusion in the subjects chemistry, physics, and biology. ...
there is considerable interest in monitoring responses to senolytic treatments. However, this has been challenging, especially at the single cell level25. In part, this is due to an imprecise definition of the heterogeneous population of senescent cells and their associated SASP which complicates appr...
This definition is motivated by simply replacing the concentration terms (inside the intracellular phase, cσ) appearing in the non-linear reaction term in Eq. (9) with the intrinsic average concentration, 〈cβ〉β, in the one-equation model. It is apparent that this definition needs a ...
the definition of the “extremely stable proteins” is somehow arbitrary when performed without exact knowledge of the other protein lifetimes. For example, our large collection of lifetimes allowed us to distinguish between LLPs (roughly between the 95th and 98th percentile most stable proteins) and...
from the following description when considered in connection with the accompanying figures. It is to be expressly understood, however, that each of the figures is provided for the purpose of illustration and description only and is not intended as a definition of the limits of the present ...