Results show that immobilized LP80 (pCBH1) is able to effectively break down the conjugated bile acids into glycodeoxycholic acid (GDCA) and taurodeoxycholic acid (TDCA) with bile salt hydrolase (BSH) activities of 0.17 and 0.07 渭mol DCA/mg CDW/h, respectively. The deconjugation product, ...
Objective: Through the antegrade perfused model of isolated neonatal rabbit, the present study aims at investigating the possible mechanisms and effects of conjugated cholic acid, within the range of concentrations of total bile acids in the serum of gravida with Intrahepatic Cholestasis of Pregnancy (...
摘要: Discusses bile acid deconjugation by lactobacilli and its effects in patients with a short small bowel (SSB). Relationship between intestinal bacteria and bile acids; Management of bile acid deconjugation in SSB patients; Effect of lactobacilli in SSB patients.关键词:...
Seminars in Nuclear MedicineCoates, G, Garnett, ES, Webber, CE (1982) Detection of deconjugation of bile salts with a 14CO2 breath test. Semin Nucl Med 12: pp. 99-100Coates G, Garnett ES, Webber CE (1982) Detection of deconjugation of bile salts with a 14CO2 breath test. Semin Nucl...
This inhibition was not dependent upon the presence of bile acids but was dependent upon the concentration of G. lamblia sonicate. Heating the sonicate for 20 min at 60° C abolished the inhibitory effect; dialysis of the sonicate did not affect inhibition. We conclude that cultured G. lamblia...
Difructose anhydride III (DFAIII) is a prebiotic involved in the reduction of secondary bile acids (BAs). We investigated whether DFAIII modulates BA metabolism, including enterohepatic circulation, in the rats fed with a diet supplemented with cholic acid (CA), one of the 12α-hydroxylated ...
Deconjugation of bile acids by human intestinal bacteria implanted in germ-free rats. Lipids. 1987,22(9) :669-671.Toshiyuki Chikai,Hiroyuki Nakao,Kiyohisa Uchida.  Deconjugation of bile acids by human intestinal bacteria implanted in germ-free rats[J]. Lipids . 1987 (9)...
Bacteroides in general attacked the taurine conjugates of di-hydroxy bile acids more readily than the trihydroxy taurine conjugates. Deconjugated bile acid moieties were further modified by some resting cells, depending on the bacterial strain while no enzymatic activity other than that of BSH was ...
Discusses bile acid deconjugation by lactobacilli and its effects in patients with a short small bowel (SSB). Relationship between intestinal bacteria and bile acids; Management of bile acid deconjugation in SSB patients; Effect of lactobacilli in SSB patients....
Targeted and untargeted pathway analyses were performed to predict the systemic effects of the altered metagenome and metabolite profiles. Dietary CA supplementation was used to determine whether the observed alterations could be overcome by intestinal bile acids functioning as FXR agonists. Human and ...