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Park J, Shrestha R, Qiu C, Kondo A, Huang S, Werth M, et al. Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease. Science. 2018;360:758–63. Article CAS PubMed PubMed Central Google Scholar Wu H, Malone AF, Donnelly EL, Kirita Y, Uc...
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we analyzed the lung of mice transgenic for hACE2 (HFH4-hACE2 mice) that were intranasally infected with either SARS-CoV-2 or mock virus, as previously described [81]. Examination of lung tissues 7 days after virus challenge demonstrated that SARS-CoV-2 infection induced severe ...
SYMBOL_NAME: nt!KiShouldSoftParkElectionBePerformed+8e IMAGE_VERSION: 10.0.22621.3880 STACK_COMMAND: .cxr; .ecxr ; kb MODULE_NAME:GenuineIntel IMAGE_NAME: GenuineIntel.sys FAILURE_BUCKET_ID: IP_MISALIGNED_GenuineIntel.sys OSPLATFORM_TYPE: x64 ...
Death effector domains (DEDs) are protein–protein interaction domains initially identified in proteins such as FADD, FLIP and caspase-8 involved in regulating apoptosis. Subsequently, these proteins have been shown to have important roles in regulating
However, peroxidation of PUFA-PC, unrelated to ferroptotic death, was reduced in the Fe/ascorbate system to a greater extent than in cells treated with RSL3. Download: Download high-res image (674KB) Download: Download full-size image Fig. 3. Inhibitory effect of Fer-1 on free radical ...
The ROS generated by Pc under irradiation destroyed the aldehyde group in the dendrimer to release rapamycin, which triggered autophagy and enhanced the efficacy of PDT to inhibit tumor growth. Download: Download high-res image (2MB) Download: Download full-size image Figure 5. The self-assembled...
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