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Diabetic kidney disease (DKD) is the leading cause of end-stage kidney disease, resulting in a huge socio-economic impact. Kidney is a highly complex organ and the pathogenesis underlying kidney organization involves complex cell-to-cell interaction with
The dysregulated immune response and inflammation resulting in severe COVID-19 are still incompletely understood. Having recently determined that aberrant death-ligand-induced cell death can cause lethal inflammation, we hypothesized that this process mi
Inflammatory responses rapidly detect pathogen invasion and mount a regulated reaction. However, dysregulated anti-pathogen immune responses can provoke life-threatening inflammatory pathologies collectively known as cytokine release syndrome (CRS), exem
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itinerary gives tourists enough time to explore top sites at a leisurely pace, which is highly recommended. Kanchanaburi is home to some of Thailand’s most historic and famous landmarks, like theBridge Over the River Kwai, as well as some of the most stunning scenery inErawan ...
However, peroxidation of PUFA-PC, unrelated to ferroptotic death, was reduced in the Fe/ascorbate system to a greater extent than in cells treated with RSL3. Download: Download high-res image (674KB) Download: Download full-size image Fig. 3. Inhibitory effect of Fer-1 on free radical ...
Download: Download full-size image Figure 1. Schematic illustration of mechanisms and designing principles of cancer therapy based on non-apoptotic cell death comprising ferroptosis, necroptosis, pyroptosis, autophagy, paraptosis, lysosome-dependent cell death and oncosis. 2. Ferroptosis and its inducers...