Emerging mechanisms of lipid peroxidation in regulated cell death and its physiological implications Yongxin Zheng Junlu Sun Yongbo Huang Review ArticleOpen Access26 Nov 2024 Microglial cannabinoid receptor type II stimulation improves cognitive impairment and neuroinflammation in Alzheimer’s disease mice by...
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Apoptosis, in biology, a mechanism that allows cells to self-destruct when stimulated by the appropriate trigger. Apoptosis can be triggered by mild cellular injury and by various factors internal or external to the cell; the damaged cells are then dispo
Tumour evolution is a complex process with many interplaying mechanisms and factors, among these is apoptosis (programmed cell death). Disabling of apoptotic responses might be a crucial contributor not only of tumour cell survival but also the resistance to the anticancer therapy. Initiation of apop...
Cell Death & Disease: 宫颈癌的治疗靶点或探明?从国自然偏爱的「铁死亡」+「线粒体」入手 铁死亡是一种非凋亡、依赖铁的调节性细胞死亡形式。当细胞内脂质活性氧水平超过谷胱甘肽依赖性过氧化物酶的抗氧化活性,导致细胞氧化还原稳态被破...
近日,来自香港大学的研究员们在Nature出版集团旗下刊物《Cell Death & Disease》发表了题为“Non-alcoholic fatty liver disease promotes breast cancer progression through upregulated hepatic fibroblast growth factor 21”的研究论文,...
Cell death has physiological and pathological functions. However, infection, chronic inflammation and tissue damage lead to sudden death of a large number of cells and then the release of large amount of cellular content into the extracellular space causes damage to the organ [4]. Cell death can...
Which factors define the differential sensitivity of distinct skin stem cells to cell death? Is there a role for non-apoptotic cell death programmes in hair cycling regulation? Can we manipulate cell death responses to improve cutaneous wound healing, while preventing tumorigenesis?
Is autosis a subtype of autophagic cell death or does all autophagic cell death occur by autosis? Does autosis occur under other pathophysiological conditions? What are the biological and clinical implications of autosis? Programmed cell death is a highly regulated cellular response in metazoans to co...