et al. Cellular cytotoxicity is a form of immunogenic cell death. J. Immunother. Cancer 8, e000325 (2020). Article PubMed PubMed Central Google Scholar Jaime-Sanchez, P. et al. Cell death induced by cytotoxic CD8+ T cells is immunogenic and primes caspase-3-dependent spread immunity ...
Ferroptosis is characterized by iron-catalyzed intracellular accumulation of lipid hydroperoxides, and it is a distinct non-apoptotic form of regulated cell death [23]. Wang et al. have found that tubulouinterstitial GPX4 expression level, a marker of ferroptosis, was correlated with human DKD ...
While the effects of death per se on gene expression are distinct from those of increasing PMI, we found a number of genes involved in the assembly of DNA, nucleosome and chromatin that were affected by both. Expression changes of these genes suggest a possible form of gene regulation through...
Movie S4. 293T Cells Expressing an Inactive Form of NT Fragment (mGSDMD-1 to -225), Related to Figure 7. The experiment was conducted as described in Movie S1, except that the cells were transfected with FLAG-hGSDMD-1 to -225. Download: Download Acrobat PDF file (10MB) Document S2. ...
There was striking neutrophilic inflammation along the nasal turbinates, the cribri- form, and in the ears in a subset of HET and CKO mice. There was also significant necrosis in the teeth and oral cavity, which could have contributed to a localized neutrophilic inflam- matory response. The...
The SDY Case Registry also received information from local sources, including the death scene report including the Sudden Unexpected Infant Death Investigation Reporting Form (SUIDIRF) if the child was under the age of 1, the autopsy, birth certificates, death certificates, records from law ...
Ester form of 24S-OHC inhibits amyloid-β production at physiological concentration while at high concentration it induces non-apoptotic programmed cell death in neuronal cells with low expres- sion of caspase-8; hence, controlling the level of 24S-OHC may prevent onset of progressive ...
McLean8, Anthony R. White9, Paul S. Donnelly2, Ashley I. Bush5 and Peter J. Crouch1* Abstract Background Ferroptosis is a form of regulated cell death characterised by lipid peroxidation as the terminal end- point and a requirement...
Also, we even did not know which form of cell death dominates the cytotoxi- city of ZnONPs for the neurons. Do these forms of cell death all or partially exist in response to ZnONPs exposure? Is ferroptosis independent of other known cell death path- ways? These questions and related ...
As may be inferred from protein docking experiments, the R70Q mutant tetramers may form an extra hydrogen bond with R54 of IRAK-4 tetramers, but loose the R70 interaction points with IRAK-2. In line with its increased IRAK-4 interaction, the R70Q mutant displayed hyperactivity towards IL-...