US Department of Health Education and Welfare and National Center for Health Statistics. Manual of the International Statistical Classification of Diseases, Injuries, and Causes of Death: Adapted for Use in the United States, Eighth Revision. Washington, DC: Public Health Service; 1967 4. World Hea...
Historic trends in mortality show seasonality in the number of deaths throughout the year, with the number of deaths higher in the winter and lower in the summer. The eFigure in the Supplement shows that death counts by week from 2015 to 2019 followed a normal seasonal pattern, with higher...
For visualization of the loading control, the APEX1 transferred PVDF membrane was incubated with HRP-conjugated rabbit anti-human APEX1 antibody (1:2000, Catalog No. LS‑C428306, LSBio, Seattle, WA) for 1 h, followed by chemiluminescent substrate and exposed for detection. Statistics and ...
oligodendrocyte cell death following contusive spinal cord injury Y Tsenkina1,3, J Ricard1,2,3, E Runko1, MM Quiala- Acosta1, J Mier1 and DJ Liebl*,1 We demonstrate that EphB3 receptors mediate oligodendrocyte (OL) cell death in the injured spinal cord through dependence receptor ...
Effect of Clostridium difficile toxin A on human colonic lamina propria cells: early loss of macrophages followed by T-cell apoptosis. Infect Immun 1998; 66: 5462–5469. 60. Monack DM, Mecsas J, Bouley D, Falkow S. Yersinia-induced apoptosis in vivo aids in the establishment of a ...
Cannabinoid regulation of glucose utilization might be important for glial and neuronal cell function in nu- merous pathophysiological conditions. For example, dur- ing ischemia, when energy metabolism is severely im- paired, lactate produced by astrocytes may serve as an endogenous neuroprotective ...
Reverse transcription-PCR (RT-PCR) strategies followed by sequencing allowed us to identify three AChE splice variants in human GCs: the readthrough (R), erythrocyte (E) and synaptic (S) AChE variant (Figures 2a–c). They were identified in GCs at different days of culture in six experiment...
Moreover, the changes in LAMP-2A content corresponded with changes in lysosomal cathepsin B proteolytic activity (Fig. 1D). We observed a robust increase in the cathepsin B activity at 4 and 8 weeks, while a negligible increase in the activity was observed at 12 weeks (Fig. 1D) followed ...
16-22 Friedman et al20 followed the prospective cohort of Terman et al23 of primarily White, gifted children growing up in California and found that childhood conscientiousness and social dependability were associated with longevity. Loeber et al12 studied factors associated with homicide death in ...
(TRAIL) selectively kills various cancer cell types, but also leads to the activation of signaling pathways that favor resistance to cell death. Here, we investigated the as yet unknown roles of calcium signaling and autophagy regulatory proteins during TRAIL-induced cell death in leukemia cells. ...