Christopher M TrainiMin WangUSUS5989858 * 1997年10月28日 1999年11月23日 Smithkline Beecham Corporation Dead-type ATP-dependent RNA helicase (DbpB) from Staphylococcus aureusUS5989858 * Oct 28, 1997 Nov 23, 1999 Smithkline Beecham Corporation Dead-type ATP-dependent RNA helicase (DbpB) from ...
DEAD box proteins use ATP to unwind short duplex RNA in an unusual fashion and remodel RNA–protein complexes, but they can also function as ATP-dependent RNA clamps to provide nucleation centres that establish larger RNA–protein complexes. Structural, mechanistic and molecular biological studies ...
Keywords:RNAhelicase;DEAD boxRNAhelicase;neoplasm 1 引言 RNA解旋酶有 9个保守基序,其中含有能够结 合 RNA和 NTP的结构域.RNA解旋酶与 RNA结 合后可以激活 NTP酶的活性,水解 NTP产生能量促 使双链 RNA解链.DEAD boxRNA解旋酶(DEAD boxRNAHelicase,DDX)是 RNA解旋酶超家族成员 之一,因为其第二个基序含有...
DDX3 is a highly conserved member of ATP-dependent DEAD-box RNA helicases with multiple functions in RNA metabolism and cellular signaling. Here, we describe a novel function for DDX3 in regulating the mitochondrial stress response in the parasitic protozoanLeishmania.We show that genetic inactivatio...
DEAD-box proteins catalyze the ATP-dependent unwinding of RNA duplexes. The common unit of these enzymes is a helicase core of two flexibly linked RecA domains. ATP binding and phosphate release control opening and closing of the cleft in the helicase core. This movement coordinates RNA-binding...
transcriptional level. RNA helicases are involved in the formation of cytoplasmic ribonucleoprotein (RNP) granules and RNA silencing. A highly conserved central domain is characteristic of DEAD-box RNA helicases and determines their basic biological activity in ATP-dependent unwinding of short RNA ...
DDX43 is an ATP-dependent RNA helicase According to its primary protein sequence, DDX43 belongs to the DEAD-box protein family of RNA helicases (16); thus we started to characterize its RNA unwinding activity. Using a 5′-tailed 13-bp duplex RNA that is commonly used with the DEAD-box ...
thaliana DEAD-box ATP-dependent RNA helicase 7 (also known as AtRH7; AT5G62190) was previously shown experimentally to be localized to the nucleus (Lorković et al. 1997). This evidence supports our phylogenetic analysis suggesting that GUCT-containing RNA helicases are clearly organelle ...
DEAD框肽5(DDX5)重组蛋白 Recombinant DEAD Box Polypeptide 5 (DDX5) G17P1; HLR1; HELR; HUMP68; p68; Asp-Glu-Ala-Asp Box Polypeptide 5; Probable ATP-dependent RNA helicase DDX5 物种 Homo sapiens (Human
DDX19B; Dbp5; DDX19; DEAD box protein 19B; DEAD box RNA helicase DEAD5; helicase DEAD5; DD19B_HUMAN; ATP-dependent RNA helicase DDX19B; DEAD box RNA helicase DEAD5; DBP5; TDBP. 产品介绍: 以保守的基序Asp-Glu-Ala-Asp(DEAD)为特征的DEAD盒蛋白是推定的RNA解旋酶。 它们涉及许多涉及RNA...