These results suggest that, W-7 in the range of 1–20 μM inhibited de novo synthesis of cholesterol and the secretion of both de novo synthesized and preformed lipids.doi:10.1016/j.bbalip.2004.02.002Mehdi RasouliCIHR Group on Molecular and Cell Biology of Lipids, Departments of Pediatrics ...
A disruption of stearoyl-CoA desaturase 1 reveals a crucial role in the de novo synthesis of hepatic cholesterol esters and triglyceridesMiyazaki, MakotoNtambi James, M
Inflammatory stress exacerbates hepatic cholesterol accumulation via increasing cholesterol uptake and de novo synthesis Inputs to the Active Indole-3-Acetic Acid Pool: De Novo Synthesis, Conjugate Hydrolysis, and Indole-3-Butyric Acid b-Oxidation ...
De novo cholesterogenesis in pregnancy J. Lab. Clin. Med., 101 (1983), pp. 256-263 View in ScopusGoogle Scholar 13. Winkel C.A., J.M. Snyder, P.C. MacDonald, E.R. Simpson Regulation of cholesterol and progesterone synthesis in human placental cells in culture by serum lipoproteins ...
(p = 0.0008) and indicated that host cellularde novosynthesis of cholesterol is upregulated byB. besnoitiinfection (Table1). In contrast to indicators of endogenous cholesterol synthesis, most oxysterols representing downstream metabolites were not found changed in their sterol:cholesterol ratios....
Mutations associated with autism often occur de novo rather than through inheritance. adjective occurring or arising spontaneously or independently of external forces; spontaneous:de novo synthesis of steroids from cholesterol. de novo mutations;
The amino-acid sequence of a protein encodes information on its three-dimensional structure and specific functionality. De novo design has emerged as a method to manipulate the primary structure for the development of artificial proteins and peptides wit
Significant differences also were observed between day 7 and 12 in total and de novo synthesis of cholesterol (p < 0.05, Table 1). No significant interaction term between female group (PCOS vs control) and time (day 7 vs day 12) was observed in any of the analyzed FAs. At day 12...
cholesterol metabolism is a broad property of phylogenetically diverse Oscillibacter spp., with potential benefits for lipid homeostasis and cardiovascular health. 越来越多的证据表明心血管疾病(CVD)与肠道微生物组的改变有关。由于缺乏与诊断生物标志物...
Fatty acid synthesis pathways were identified as the most significantly enriched pathways by Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis (Fig. 3A). GO enrichment showed that secondary alcohol, cholesterol, steroid, and sterol biosynthesis were the main biological processes that were altered...