1.PEAKS: PEAKS软件是一款广泛使用的De Novo测序工具,它能够处理不同类型的质谱数据,并提供准确的氨基酸序列预测和修饰位点鉴定。 2.Novor: Novor是一种基于深度学习算法的De Novo测序工具,具有较高的准确性和灵敏度,适用于复杂样本的分析。 3.PepNovo: PepNovo是一款开源的De Novo测序软件,支持不同类型的质谱数据...
所以肽段recall 更能体现它的性能。故使用SMSNet不进行rescoring的情况分别与PointNovo是否搭载LSTM模块的...
De novo sequencing software has been widely used in proteomics to sequence new peptides from tandem mass spectrometry data. This study presents a new software tool, Novor, to greatly improve both the... 关键词: Peptide de novo sequencing Tandem mass spectrometry Software Real time Decision tree ...
图2. 充分利用de novo测序 的标准PEAKS Studio工作流程 参考文献 1.Tran NH, Qiao R, Xin L, Chen X, Liu C, Zhang X, Shan B, Ghodsi A, Li M. Deep learning enablesde novopeptide sequencing from data-independent-acquisition mass spectrometry. Nature Methods. 16(1), 63-66. 20/12/2018. 2...
全基因组测序分为从头测序(de novo sequencing)和重测序(re-sequencing)。 从头测序(de novo)不需要任何参考基因组信息即可对某个物种的基因组进行测序,利用生物信息学分析方法进行拼接、组装,获得该物种的基因组序列图谱,从而推进该物种的后续研究。 基因组重测序是对有参考基因组物种的不同个体进行的基因组测序,并...
全基因组测序分为从头测序(de novo sequencing)和重测序(re-sequencing)。 从头测序(de novo)不需要任何参考基因组信息即可对某个物种的基因组进行测序,利用生物信息学分析方法进行拼接、组装,获得该物种的基因组序列图谱,从而推进该物种的后续研究。 基因组重测序是对有参考基因组物种的不同个体进行的基因组测序,并...
Here we present GlycanFinder, a database search and de novo sequencing tool for the analysis of intact glycopeptides from mass spectrometry data. GlycanFinder integrates peptide-based and glycan-based search strategies to address the challenge of complex
This study focuses on the Illumina sequencing platform that produces millions of very short sequences that are 35 bases in length. We propose a de novo assembler software that is dedicated to process such data. Based on a classical overlap graph representation and on the dete...
最后,牟合蛋白科技有限公司团队首发的蛋白质De novo sequencing,即蛋白质从头测序(也称全新蛋白测序),其不依赖任何蛋白质数据库,不遗漏可能肽段、点突变及未知修饰的特点突破了传统质谱测序的局限,测序覆盖率高,可与AlphaFold完美结合,对未知蛋白作出结构预测,打开蛋白质结构预测的新世界。
MIDDAS-M: Motif-Independent De Novo Detection of Secondary Metabolite Gene Clusters through the Integration of Genome Sequencing and Transcriptome Data Many bioactive natural products are produced as "secondary metabolites" by plants, bacteria, and fungi. During the middle of the 20th century, several...