2010. De novo fatty acid synthesis and balance of fatty acids of pigs fed different fat sources. Livest. Sci. 132:157-164.Duran-Montge, P.; Realini, C.E.; Barroeta, A.C.; Lizardo, R.G.; Esteve-Garcia, E. De novo fatty acid synthesis and balance of fatty acids of pigs fed ...
The objective of this study was to evaluate the relationship between ruminal pH and milk de novo fatty acid (DNFA) concentrations determined by Fourier-transform infrared spectroscopy. Data were collected from 18 multiparous Holstein cows fitted with a rumen cannula and fed 1 of the experimental ...
It was hypothesized that the feeding of PUFA instead of SFA would inhibit whole-body de novo fatty acid synthesis. As indexes of de novo fatty acid synthesis, we used the concentration of plasma triacylglycerols and minimum fatty acid synthesis calculated as fatty deposition minus digestible fatty ...
Although TH17 cells use this pathway to produce phospholipids for cellular membranes, Treg cells readily take up exogenous fatty acids for this purpose. Notably, pharmacologic inhibition or T cell–specific deletion of ACC1 not only blocks de novo fatty acid synthesis but also interferes with the ...
Importantly, the inhibition of fatty acid synthesis arrested the cells at G2/M despite the presence of abundant fatty acids in the media. Our results suggest that de novo lipogenesis is essential for cell cycle completion. This lipogenic checkpoint at G2/M may be therapeutically exploited for ...
These observations suggest that enzymes in the lipid synthesis pathway would be rational therapeutic targets for cancer. To this end, we review the enzymes inde novofatty-acid synthesis and related pathways.关键词: lipid metabolism fatty-acid synthase acyl-CoA synthetase ...
1690 EFFECTS OF EXOGENOUS PALMITATE ON DE NOVO FATTY ACID SYNTHESIS IN FETAL LUNG EXPLANTSfatty acid synthesis in fetal lung is probably an important source of the long chain fatty acid constituents of pulmonary surfactant and membrane phospholipids. In some tissues,fatty acid synthesis is regulated,...
Pathway analysis related these genes to biological functions and canonical pathways controlling lipid and fatty acid metabolisms. In concordance with the phenotypic classification of animals, the major metabolic pathway differentially modulated between groups was de novo lipogenesis, the group with more ...
4. 4. The ratio of total radioactivity to radioactivity in carboxyl carbon of the synthesized fatty acids indicated that a de novo mechanism of fatty acid synthesis is operative in eel-liver cytosol.doi:10.1016/0305-0491(90)90263-SGabriele V. Gnoni...
de novo fatty acids milk fat milk protein INTRODUCTION De novo milk fatty acids (FA; C4 to C14) are those that are synthesized in the cow's mammary gland using acetate and butyrate—VFA that originate from the fermentation of fibrous feeds in the rumen (Palmquist et al., 1993). Mixed-or...