Antimicrobial resistance (AMR) poses a severe threat to global health. The wide distribution of environmental antibiotic resistance genes (ARGs), which can be transferred between microbiota, especially clinical pathogens and human commensals, contributed significantly to AMR. However,...
Antibiotic resistance genes (ARGs) are emerging pollutants present in various environments. Identifying ARGs has become a growing concern in recent years. Several databases, including the Antibiotic Resistance Genes Database (ARDB), Comprehensive Antibiotic Resistance Database (CARD), and Structured Antibio...
Current open challenges include the spread of chemicals and biological contaminants (e.g. viral genetic material, antibiotic resistance genes and bacteria). The occurrence and the effects of these new type of contaminants is unknown. The NORMAN ARB&ARGs database is an effort to aggregate ...
Antibiotic resistance,which is encoded by antibiotic-resistance genes(ARGs),has proliferated to become a growing threat to public health around the world.With technical advances,especially in the popular-ization of metagenomic sequencing,scientists have gained the ability to decipher the profiles of ARGs...
The CARD integrates disparate molecular and sequence data, provides a unique organizing principle in the form of the Antibiotic Resistance Ontology (ARO), and can quickly identify putative antibiotic resistance genes in new unannotated genome sequences. This unique platform provides an informatic tool ...
This pipeline is distributed in the hope to achieve the aim of management of antibiotic resistant genes in environment, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.This pipeline is only allowed to be used for non-commercial and...
This pipeline is distributed in the hope to achieve the aim of management of antibiotic resistant genes in environment, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.This pipeline is only allowed to be used for non-commercial and...
Signal transduction systems regulate the majority of cellular activities including the metabolism, development, host-recognition, biofilm production, virulence, and antibiotic resistance of human pathogens. Thus, knowledge of the proteins and interactions that comprise these communication networks is an ...
The discovery of new genes and proteins identified through metagenomics approaches includes the first bacteriorhodopsin of bacterial origin, novel small molecules with antimicrobial activity, and antibiotic resistance determinants. The assembly of multiple genomes in an environmental sampling, for instance, ...
The SARS-CoV-2 genome is made of less than 30000 nucleotides and contains genes for 29 different proteins9. The ORF1ab alone encodes as many as 16 non-structural proteins10. Some of the key proteins encoded by this gene are PLpro (NSP2), 3CLpro (NSP5), RdRp (NSP12), and helicase...