Heterozygous mice that express Cre-recombinase under the dopamine transporter promoter (DAT-Cre knock in mice, or KI) are widely used for targeting midbrain dopamine neurons, under the assumption that their con
Subtle impact of the reduction in dopamine transporter (DAT) gene expression in DAT-Cre miceMingote, SusanaChohan, M OChuhma, NGellman, CeliaInbar, BRayport, SMoore, H M
DAT-Ires-Cre and TH-Cre mice bred on mixed 129S6/C57BL/6 and pure C57BL/6 backgrounds were evaluated for novelty-induced, baseline, and amphetamine (AMPH)–induced locomotion, and for AMPH and D1 agonist (SKF-38393)–induced preservative behaviors. ...
In the inner nuclear layer (INL) of TH-Cre Ai9 mice, a dense population of TH-negative cells expressed tdTomato (tdT), in addition to sparse subsets of dopaminergic ACs (DACs, TH-positive) and starburst ACs (SACs) (Figures 1A and S1) (Vuong et al., 2015). The cell bodies of the...
These strategies have been rapidly and widely adopted, particularly in the study of gene-modified and transgenic mice. In addition, Cre's modest biochemical requirements have led to the adoption of Cre for use in...
Correction to: Altered baseline and amphetamine-mediated behavioral profiles in dopamine transporter Cre (DAT-Ires-Cre) mice compared to tyrosine hydroxylase Cre (TH-Cre) miceA Correction to this paper has been published: https://doi.org/10.1007/s00213-020-05718-2...
Effect of pretreatment with AP5 in the VTA on the development of behavioral sensitization to cocaine in NR1DATCre mice.Yu LuoCameron H. GoodOscar DiazRuizYaJun ZhangAlexander F. HoffmanLufei ShanSerena Y. KuangNasir MalikVladimir I. Chefer...
Dendritic stratification of labeled neurons is found at the center of IPL and identical in mice obtained in 2010 and 2015. These cells do not spike and transiently depolarize at both light onset and offset. L-AP4 blockade or genetic removal of the ON-pathway in the Nob background eliminates ...
METHODS: Adenovirus expressing Cre-recombinase (Adeno-Cre) was intraductally injected into the prostate of ROSA26 reporter mice. Immmunohistochemical and X-gal staining were performed on prostate tissue sections harvest...