Subtle impact of the reduction in dopamine transporter (DAT) gene expression in DAT-Cre miceMingote, SusanaChohan, M OChuhma, NGellman, CeliaInbar, BRayport, SMoore, H M
Sex-dependent alterations in behavior, drug responses and dopamine transporter expression in heterozygous DAT-Cre mice_2021_Kau 上传人:dvrg01f23·上传时间:2022-10-22 0% 0% 0% 0% 0% 继续阅读
Heterozygous mice that express Cre-recombinase under the dopamine transporter promoter (DAT-Cre knock in mice, or KI) are widely used for targeting midbrain dopamine neurons, under the assumption that their constitutive physiology is not affected. We rep
DAT-Ires-Cre and TH-Cre mice bred on mixed 129S6/C57BL/6 and pure C57BL/6 backgrounds were evaluated for novelty-induced, baseline, and amphetamine (AMPH)–induced locomotion, and for AMPH and D1 agonist (SKF-38393)–induced preservative behaviors. Results DAT-Ires-Cre mice on both mixed...
Correction to: Altered baseline and amphetamine-mediated behavioral profiles in dopamine transporter Cre (DAT-Ires-Cre) mice compared to tyrosine hydroxylase Cre (TH-Cre) miceA Correction to this paper has been published: https://doi.org/10.1007/s00213-020-05718-2...
While SMN expression was robust in the central nervous system as expected, SMA mice did not live longer. Weight and time-to-right motor function were not significantly improved.doi:10.1007/s11248-013-9702-yHerbert BosTran...
Our DAT-Cre specific primers do not pick up other Cre drivers. Dendritic stratification of labeled neurons is found at the center of IPL and identical in mice obtained in 2010 and 2015. These cells do not spike and transiently depolarize at both light onset and offset. L-AP4 blockade or ...
Effect of pretreatment with AP5 in the VTA on the development of behavioral sensitization to cocaine in NR1DATCre mice.Yu LuoCameron H. GoodOscar DiazRuizYaJun ZhangAlexander F. HoffmanLufei ShanSerena Y. KuangNasir MalikVladimir I. Chefer...
DAT-Flp mice can be used with various Cre-expressing mouse lines to efficiently and selectively label dopaminergic subpopulations using Cre/Flp-dependent intersectional strategies. We demonstrate the utility of this approach by crossing DAT-Flp mice with NEX-Cre mice, to specifically label Neurod6-...
MiceDiscusses the contribution of TH-CRE, a species of genetically modified mice from the Institute of Research on Genetic Engineering and Molecular Biology in Buenos Aires, Argentina, to medicine. Uses of the mice for the global medicine and science research.Ramos, ...