基因名 Th 基因曾用名 - 染色体位置 7 NCBI ID 21823 MGI ID 98735 Ensembl ID ENSMUSG00000000214 Pubmed Th 人类同源基因 TH 品系描述 将IRES-creER插入到小鼠Th基因终止密码子处。 应用领域:Cre工具鼠,脑内多巴胺能神经元等区域 *使用本品系发表的文献需注明: Th-IRES-CreERT2 mice (Cat. NO. NM-KI-200...
DAT-Ires-Cre and TH-Cre mice bred on mixed 129S6/C57BL/6 and pure C57BL/6 backgrounds were evaluated for novelty-induced, baseline, and amphetamine (AMPH)–induced locomotion, and for AMPH and D1 agonist (SKF-38393)–induced preservative behaviors. Results DAT-Ires-Cre mice on both mixed...
Modulation of hypothalamic hunger circuits by a catecholaminergic pathway in TH-cre transgenic miceAklan, ltanAtasoy, Nilüfer SayarYavuz, YavuzAte, Tayfunoban, lknurFiliz, GizemAlkan, Fulya KksalarTopu, skalen Cansuncül, MerveDilsiz, Pelin...
Also, in animal studies, it has been shown that low pH in the skin acts on nociceptors, exciting them and thus contributing to pain sensitivity (Steen et al., 1995), and in the case of the TrkCCreERT2 mice, this could be the result of the hypoxia generated by vasoconstriction. ...
Our data show the following: (1) Insertion of Cre-recombinase into the Pnmt locus created a functional knockout of Pnmt expression with concomitant loss of epinephrine in homozygous Pnmt Cre/Cre mice; (2) Despite the reduction in Pnmt expression and epinephrine production in Pnmt Cre/Cre mice,...
osteoarthritismiR-1Indian hedgehogtransgenic miceThe present study assessed the effects of microRNA?1 (miR?1) on the development of osteoarthritis using human tissues and a Col2a1?Cre?ERT2/GFPfl/fl?RFP?miR?1 mouse model of osteoarthritis. Human cartilage tissues (n=20...