The daf-2 Gene Acts in the Adult to Limit Life SpanPl, LarsenDl, Riddle
Mutations in the daf-2 gene, which encodes a member of the insulin receptor fam... Y Honda,S Honda - 《Faseb Journal》 被引量: 2065发表: 1999年 Shared Transcriptional Signature in Caenorhabditis elegans Dauer Larvae and Long-lived daf-2 Mutants Implicates Detoxification System in Longevity ...
为"生物钟"基因(clockgene,clk),它们可以碱慢发 育,延长细胞周期,调节成年线虫行为等.clk1基因 编码一个82个氨基酸残基的异常的细胞溶质过氧 化氢酶,它在真核细胞生物中高度保守.目前,线虫 中寿限最长的是dM一2/elk一1双突变体.它是普通线 虫寿限的5～6倍.这个突变体中,细胞溶质过氧化 ...
·68· 国外医学分子生物学分册2001年第23卷第2期 daf一2和daf一16基因的结构与功能研究进展 吴予平综述 赵利淦审阅 暨南大学生命科学技术学院(广州,510632) 摘要 在长寿和衰老的研究中,人们发现调控休眠态的幼虫形成的基因(daf基因)能影响线虫的长寿。其中 daf一2、daf一16是作用于这一遗传调控通路下游的两个重...
Twenty-nine years following the breakthrough discovery that a single-gene mutation of daf-2 doubles Caenorhabditis elegans lifespan, it remains unclear where this insulin/IGF-1 receptor gene is expressed and where it acts to regulate ageing. Using knock-
There are two similar genes in the bodies of mammals.By changing the function of on gene,scientists extended the life of a mouse by 1 8 per cent(or 4.5 months).Another gene is called IGF-1.Researchers still don’t know how it affects our body.But by reducing its functions the life of...
上海懋康生物科技有限公司是一家涉足于生命科学和生物技术领域研究的试剂、仪器和实验室消耗品与实验服务工作,主要从事细胞生物学、植物学、分子生物学、免疫学、生物化学、蛋白组学。生物制药与诊断试剂研发生产等领域。 本公司秉承“以人为本,以诚为信、合同守信”的经
Our results provide evidence that alternative splicing regulation of a single critical gene in a single critical neuron is essential for learning ability in an organism. Little is known about the molecular mechanisms regulating neuron-specific alternative splicing. Here, the authors identify a ...
#新品#【新品速递:GeneScope】探索荧光原位杂交技术的起源 用途:A sensitive and specific fluorescent indicator for the direct detection of nitric oxide (NO) in vitro 产地:上海 CAS编号:205391-01-1 品牌:爱必信(absin) 包装规格:1mg 货号:abs42016242 ...
| addgene | ademtech | adg | adi | adipogen | adooq | advanced bioscience laboratories, inc | advanced biotechnologies | advanced biotechnologies incorporated | Advanced Ceramics Manufacturing | advanced chemtech | Advanced Environmental Solutions Inc. | advanced immunochemical | advanced immunochemical in...