Of note, the worms in which DAF-2 was degraded throughout the body had a lifespan that was 266.5% of the WT (Fig.3h), outliving the canonical hypomorphicdaf-2(e1370)mutant and the intestinal DAF-2 AID worms, whose lifespans were 206.0% and 193.3% of the WT, respectively (Fig.3h)...
daf-2(e1370) animals are developmentally delayed by approximately 24 h and have reduced fecundity with an extended reproductive period. Importantly, at the restrictive temperature of 25 °C, daf-2(e1370) animals go into an alternative life state known as “dauer diapause” which prevents entry ...
To identify relevant DAF-16/FOXO targets, we performed a PSG-specific gene profiling analysis by extracting RNA from isolated PSG cells of a daf-2-reduction-of-function (rf) mutant, daf-2(e1370) (high DAF-16/FOXO activity) and a daf-16(0); daf-2(rf) double mutant with a null ...
Notes: survival curves of mutants under Cr (VI)-induced oxidative stress conditions: (a) eat-2 (ad465); (b) rsks-1 (ok1255); (c) isp-1 (qm150); (d) nuo-6 (qm200); (e) glp-1 (e2144); (f) daf-16 (mu86); (g) daf-2 (e1370); and (h) age-1 (hx546), ...
【题目】如图,△ABC和△ADE均为等腰直角三角形,∠BAC=∠DAE=90°,B、C、E三点共线,连接DC,点F为CD上的一点,连接AF. (1)若BE平分∠AED,求证:AC=EC; (2)若∠DAF=∠AEC,求证:BE=2AF. 试题答案 在线课程 【答案】(1)见解析;(2)见解析. ...
当H2在O-2c(图5d,e)和 O-3c 位点处与含空位的结晶态c-TiO2-x表面相互作用时,H2不能解离形成OH。在同时存在H2和CO2的情况下,在1307 cm-1、1370 cm-1和1677 cm-1处的峰(图5f),可归为羧酸盐物种。甲酸盐物种的峰值强度在高温 (200 → 300 °C) 下...
(2)耳聋 耳蜗血管病变导致缺血与缺氧的基础上,病变呈持续性、进行性加重,会发生听神经退行性病变(听力早衰),在早期耳鸣的基础上,会进一步加重继而发生听力下降甚至于耳聋,具体原因如下: 糖尿病导致的周围神经病变耳聋 有研究表明,糖尿病...
2. 将功放的杜比解码输入插口与播放源的杜比输出插口相连。 3. 确认接口连接无误,开启杜比解码功能。 四、注意事项 1. 杜比解码功能只有在播放源和功放都支持杜比编码才可使用,否则无法打开杜比解码功能。 2. 需要保证杜比解码输入插口和杜比输出插口的接口类型一致,插头不...
中和法是制备磷酸二氢钠的传统方法之一。该方法通过磷酸与氢氧化钠或碳酸钠等碱性物质进行中和反应,生成磷酸二氢钠。具体步骤如下: 将氢氧化钠或碳酸钠放入反应釜中,加水稀释至一定浓度。 在搅拌条件下,缓慢加入磷酸,控制反应温度和pH值,使反应充分进行。 反应结束后,将反应液进行蒸发浓缩,冷...
(c) Salt concentration learning of the wild type, daf-16(mgDf50), daf-16(mgDf50); daf-2(e1370) and daf-16(mgDf50); ptb-1(gk347274); asd-1(ok2299). (d) Salt concentration learning of wild-type, daf-2(pe1230) and ptb-1(gk347274); asd-1(ok2299) worms expressing none ( ...