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Molecular Brain (2018) 11:8 https://doi.org/10.1186/s13041-018-0352-0 RESEARCH Open Access Poly-arginine R18 and R18D (D-enantiomer) peptides reduce infarct volume and improves behavioural outcomes following perinatal hypoxic-ischaemic encephalopathy in the P7 rat Adam B. Edwards1,2,3, ...
The present invention concerns a method for preventing and/or treating cancer in a patient comprising administering an effective amount of substantially purified D enantiomer of difluoromethylornithine (D-DFMO) or an analog of D-DFMO to the patient. D-DFMO or an analog thereof is administered at...
Each of the six D-analogues induced an immune response with an unusually high level of IgG3 antibodies. The D-enantiomer produced IgG3 antibodies which reacted with the homologous peptide as well as with the all L-peptide and the parent protein H3 in solution but not with analogues ...
D-Enantiomer of DFMO and methods of use thereof for treating cancer 本发明涉及在患者中预防和/或治疗癌症的方法,该方法包括向患者施用有效量的明显富集的二氟甲基鸟氨酸的D对映体(D-DFMO)或D-DFMO的类似物. The present invention relates to a method for the prevention and / or treatment of cancer ...
对映异构体(Enantiomer)是互为实物与镜像但无法完全重叠的立体异构体,具有相同的物理、化学性质,但在光学活性和生物活性上存在差异。
Ivabradine R-Enantiomer Hydrochloride (25 mg) ((R)-3-(3-(((3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one, hydrochloride) Basic information More.. Product Name: Ivabradine R-Enantiomer ...
We examined the neuroprotective efficacy of the poly-arginine peptide R18 and its D-enantiomer R18D in a perinatal hypoxic-ischaemic (HI) model in P7 Sprague-Dawley rats. R18 and R18D peptides were administered intraperitoneally at doses of 30, 100, 300 or 1000 nmol/kg immediately after ...
Kind Code: A1 Abstract: Beschrieben wird ein Peptid, umfassend eine Aminosäuresequenz ausgewählt aus der Gruppe bestehend aus SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5 SEQ ID NO: 6 oder SEQ ID NO: 7 sowie ein solches Peptid zur Verwendung...
Each of the six D-analogues induced an immune response with an unusually high level of IgG3 antibodies. The D-enantiomer produced IgG3 antibodies which reacted with the homologous peptide as well as with the all L-peptide and the parent protein H3 in solution but not with analogues ...