D-Alanyl-D-Alanine is a compound found in the partial ESI mass spectrum of a mixture containing vancomycin, acetyl-D-Alanyl-D-Alanyl-D-alanine, acetyl-D-Alanyl-D-alanine, and acetyl-glycyl-D-alanine. AI generated definition based on: International Journal of Mass Spectrometry, 2002 ...
3 & Angel Manteca1 This work contributes to the understanding of cell wall modifications during sporulation and germination in Streptomyces by assessing the biological function and biochemical properties of SCO4439, a D-alanyl-D-alanine carboxypeptidase (DD-CPase) constitutively expressed during ...
Scheme of the reaction catalyzed: D-alanyl-D-alanine + H2O <=> 2 D-alanine. The natural substrate is nascent, high molecular weight peptidoglycan. Sign in to download full-size image (A and B) Structure of the wall peptidoglycan of E. coli (A) and assembly from the lipid II intermedi...
D-Alanyl-(D)-meso-2,6-diaminopimelic acid endopeptidase was purified 47.4-fold with a yield of 40.5% from mutanolysin, which was partially purified from the cultural supernatant of Streptomyces globisporus 1829, by using ion exchange column chromatographies and a molecular sieve column. The ...
Structure of a Zn2+-containing D-alanyl-D-alanine-cleaving carboxypeptidase at 2.5 A resolution. at 2.5 resolution, of the penicillin-resistant Zn 2+ -containing D -alanyl- D -alanine peptidase of Streptomyces albus (Zn 2+ G peptidase) 3,4 . ... O Dideberg,P Charlier,G Dive,... -...
muramyl-l-alanyl- d-glutamyl-meso-diaminopimelic acid) and M-pentapeptide (N-acetylmuramyl-l-alanyl-d-glutamyl- meso-diaminopimelic acid-d-alanine-d-... Bernd,Wiedemann,Helgard,... - 《Clinical Infectious Diseases》 被引量: 53发表: 1998年 加载更多0...
A Highly active and negatively charged Streptococcus pyogenes Lysin with a Rare D-Alanyl-L-Alanine Endopeptidase Activity Protects Mice against Streptococcal Bacteremia. Lood R,Raz A,Molina H,et al. Antimicrobial Agents and Chemotherapy . 2014
B. subtilis CwlK (YcdD) exhibits high sequence similarity with the peptidoglycan hydrolytic l,d-endopeptidase (PLY500) of Listeria monocytogenes phage and CwlK has the VanY motif which is a d-alanyl-d-alanine carboxypeptidase (Pfam: http://www.sanger.ac.uk/Software/Pfam/). The β-...
Kinetic studies have shown a Km value of 0.57 mM and an apparent Kmax of 8.3 渭mol min1 (mg enzyme)1 with N-acetylmuramyl-l-alanyl-纬-D-glutamyl-(L)meso-diaminopimelyl (L)-D-[14C]alanine as substrate. The enzyme was inhibited by o-phenanthroline and EDTA and was reactivated by ...
Likewise, N-substitution of N-terminal l -alanine does not modify the enzymic specificities. Kinetic studies have shown that and are good substrates for L d -carboxypeptidase (apparent K m = 0.8 mM and 1.25 mM, respectively). is the best substrate for the endopeptidase (apparent K m = ...