The process also involves the conversion of mammalian homolog of Atg8 with microtubule-associated protein-1 light chain-3 I (LC3 I) to a PE-conjugated form, denoted LC3 II, which localizes in the autophagosomes. The formation of LC3 II is, however, not specific for autophagy but also ...
DLC1 forms a complex with EZH2 in the cytoplasm DLC1 is mainly a cytoplasmic protein7, while the impact of EZH2 on cancer is widely attributed to its canonical epigenetic regulation of gene expression resulting from its methylation of H3K27 in the nucleus17,26. It was therefore unclear whethe...
Ni-NTA nickel-nitrilotriacetic acid C1GalT1 core 1 β3galactosyltransferase COP coat-protein complex MGAT1 mannosyl α-1,3-glycoprotein β-1,2-N-acetyl-glucosaminyltransferase aa amino acid(s) Ab antibody. 3 A. Petrosyan, M. F. Ali, and P.-W. Cheng, unpublished observation. ...
Photosystem II Agricultural and Biological Sciences 100% Thylakoid Agricultural and Biological Sciences 100% Chlorophyll Binding Protein Agricultural and Biological Sciences 100% Light-Harvesting Complex Agricultural and Biological Sciences 100% Protein Binding Immunology and Microbiology 100% Light Harvest...
Here we present data showing that expression of furin promotes the first step of clathrin-coat assembly at the TGN, the recruitment of the Golgi-specific assembly protein AP-1 on Golgi membranes. Further, we report that furin indeed is present in isolated clathrin-coated vesicles. Packaging into...
Here we present data showing that expression of furin promotes the first step of clathrin-coat assembly at the TGN, the recruitment of the Golgi-specific assembly protein AP-1 on Golgi membranes. Further, we report that furin indeed is present in isolated clathrin-coated vesicles. Packaging into...
Here we present data showing that expression of furin promotes the first step of clathrin-coat assembly at the TGN, the recruitment of the Golgi-specific assembly protein AP-1 on Golgi membranes. Further, we report that furin indeed is present in isolated clathrin-coated vesicles. Packaging into...
The Spike (S) protein of SARS-CoV-2 binds ACE2 to direct fusion with host cells. S comprises a large external domain, a transmembrane domain, and a short cytoplasmic tail. Understanding the intracellular trafficking of S is relevant to SARS-CoV-2 infecti
The conformations of the core complex in these two states are very similar, except for Rrp44's RNase II- like domain, which comprises the CSD1, CSD2, RNB and S1 domains (Figure 4A). The major conformational difference between the two states occurred in the Rrp44 protein, in which the ...
(photosystem II protein D1, PsbA),mitochondrial membrane(alternative oxidase 1 [AOX1]), and plasma membrane (H+adenosine triphosphatase[H+ATPase]) gave negative results, indicating that these membrane compartments are not significant contaminants of the vesicle preparation (seeFigure S1available online...