Coat Protein Complex II (COPII) is a protein complex involved in the transport of proteins from the endoplasmic reticulum (ER) to the Golgi apparatus within cells. AI generated definition based on: Advances in Pharmacology, 2010 About this pageSet alert Also in subject areas: Medicine and Dentis...
The coat protein complex II (COPII) is a highly conserved vesiculation machinery mediating protein transport from the endoplasmic reticulum to the Golgi apparatus in eukaryotes. Intriguingly,COPII paralogues greatly outnumber those in yeast and mammals. However, the functional diversity and underlying ...
aThe coat protein complex II (COPII) forms transport vesicles from the endoplasmic reticulum and segregates biosynthetic cargo from ER-resident proteins. Recent high-resolution structural studies on individual COPII subunits and on the polymerized coat reveal the molecular architecture of COPII vesicles. ...
Secretory proteins are transported from the endoplasmic reticulum (ER) in vesicles coated with coat protein complex II (COPII). To investigate the molecular mechanism of protein sorting into COPII vesicles, we have developed an budding reaction comprising purified coat proteins and cargo reconstituted pr...
The coat protein complex II (COPII) is a highly conserved vesiculation machinery mediating protein transport from the endoplasmic reticulum to the Golgi apparatus in eukaryotes1. Intriguingly, Arabidopsis COPII paralogues greatly outnumber those in yeast and mammals2,3,4,5,6. However, the functional...
Curvature-generating proteins that direct membrane trafficking assemble on the surface of lipid bilayers to bud transport intermediates, which move protein and lipid cargoes from one cellular compartment to another. However, it remains unclear what controls the overall shape of the membrane bud once cur...
Recent studies of transport-carrier formation in the early secretory pathway have provided new insights into the mechanisms of cargo selection by coat protein complex-II (COPII) adaptor proteins, the construction of cage-protein scaffolds and fission. These studies are beginning to produce a unifying...
(2013) Switching the clientele: a lysine residing in the C terminus of the serotonin transporter specifies its preference for the coat protein complex II ... S Sucic,F Koban,A El-Kasaby,... 被引量: 0发表: 2018年 Switching the clientele: A lysine residing in the c terminus of the sero...
The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C J. Biol. Chem, 286 (2011), pp. 16482-16490 View PDFView articleView in ScopusGoogle Scholar 47 D. Bengel, D.L. Murphy, A.M. Andrews, C.H. Wichems, D. Feltner, A. Heils, R...
In the present study we investigated the mechanism by which Erv26p couples pro-ALP to the coat protein complex II (COPII) export machinery. Site-specific mutations were introduced into Erv26p, and mutant proteins were assessed in cell-free assays that monitor interactions with pro-ALP cargo ...