Coat Protein Complex II In subject area:Pharmacology, Toxicology and Pharmaceutical Science The COPII coat complex is comprised of Sar1, a small GTPase that initiates coat assembly, the cargo-binding Sec23/24 bimolecular complex, and Secl3/31, which together with Sec23/24 assemble into o...
Here, an interaction between PS1 and the Sec13 protein is described. Sec13 takes part in coat protein complex II, COPII, vesicular trafficking, nuclear pore function, and ER directed protein sequestering and degradation control. The interaction maps to the N-terminal part of the large hydrophilic...
The coat protein complex II (COPII) is a highly conserved vesiculation machinery mediating protein transport from the endoplasmic reticulum to the Golgi apparatus in eukaryotes1. Intriguingly, Arabidopsis COPII paralogues greatly outnumber those in yeast and mammals2,3,4,5,6. However, the functional...
Recent studies of transport-carrier formation in the early secretory pathway have provided new insights into the mechanisms of cargo selection by coat protein complex-II (COPII) adaptor proteins, the construction of cage-protein scaffolds and fission. These studies are beginning to produce a unifying...
At this stage, storage products, such as protein bodies, accumulate within the cells of the embryo proper. The cells of the inner seed coat (arrowhead) begin to shrivel, and the out layer of the outer seed coat (arrow) has compressed. Scale bar = 40 μm. H At maturity, the ...
Possible regulation of caveolar endocytosis and flattening by phosphorylation of F-BAR domain protein PACSIN2/Syndapin II Structural Insights into the Organization of the Cavin Membrane Coat Complex. Dev Cell 2014 ; 31:405-19; PMID: 25453557 ; http://dx.doi.org/ 10.1016... Y Senju,S Suetsug...
To accomplish this feat, the cell employs a set of conserved cytoplasmic coat proteins 鈥 the coat protein \\\{II\\\} (COPII) complex 鈥 that recruit cargo into nascent buds and deform the \\\{ER\\\} membrane to drive vesicle formation. While our understanding of \\\{COPII\\\} ...
(formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have...
5.01 software, and was performed on the amide I, side chain aromatic amino acid residues, and the amide II peaks, between 1520 and 1750 cm-1. The 1520–1750 cm-1 spectral region for each protein was peak fitted using a combination of Gaussian and Lorentzian functions (Voi...
Vesicles that are coated by coat protein complex II (COPII) are the primary mediators of vesicular traffic from the endoplasmic reticulum to the Golgi apparatus. Secretion-associated Ras-related GTPase 1 (SAR1) is a small GTPase that is part of COPII and, upon GTP binding, recruits the other...