US5916891 * Jun 7, 1995 Jun 29, 1999 Smithkline Beecham Corporation Pyrimidinyl imidazolesUS5916891 * 1995年6月7日 1999年6月29日 Smithkline Beecham Corporation Pyrimidinyl imidazolesUS5916891 Jun 7, 1995 Jun 29, 1999 Smithkline Beecham Corporation Cytokine mediated diseases...
内容提示: Cytokine-mediated cPLA 2 phosphorylation is regulated by multipleMAPK family membersNiels Geijsen, Pascale F. Dijkers, Jan-Willem J. Lammers, Leo Koenderman, Paul J. Co¡er*Department of Pulmonary Diseases, G03.550, University Medical Centre, Heidelberglaan 100, 3584 CX Utrecht, The...
These findings, using primary human neuronal cell cultures, support the hypothesis that cytokine-mediated neurotoxicity involving NO proceeds via an apoptotic mechanism. These findings could lead to the development of new therapies for neurodegenerative diseases involving glia, cytokines, and NO. 展开 ...
1,4-Benzofused urea compounds useful in treating cytokine mediated diseases 来自 百度文库 喜欢 0 阅读量: 28 申请(专利)号: US10369847 申请日期: 20030219 公开/公告号: US20030232865A1 公开/公告日期: 20031218 申请(专利权)人: BOEHRINGER INGELHEIM PHARMACEUTICALS INC.发明人:...
Interleukin 12 (IL-12) is a heterodimeric cytokine produced primarily by antigen-presenting cells (APCs) which plays a key role in promoting type 1 T helpe
We and others identified rare loss-of-function variants in X-chromosomal TLR7 in young men with severe COVID-19 and with no prior history of major chronic diseases, that were associated with impaired TLR7 signaling as well as type I and II IFN responses. Here, we performed RNA sequencing ...
T-cell targeted therapies in autoimmune diseases T-cell-mediated immune dysregulation occurs in a variety of autoimmune conditions, including rheumatoid arthritis, inflammatory bowel disease, and multiple ... F Alnaimat,P Sidhu,S Sarkar - 《Drug Development Research》 被引量: 45发表: 2011年 加载更...
This cell death process has recently been implicated in several disorders such as neurodegenerative diseases [24,26,27] and ischemia/reperfusion injuries [14,16,42], which are characterised by both inflammation and massive ROS production [[43], [44], [45], [46]]. In particular, pancreatic ...
摘要: Targeting apoptosis to treat diseases has seen tremendous success over the past decades. More recently, alternative forms of regulated cell death, including pyroptosis and necropto... 查看全部>>收藏 引用 批量引用 报错 分享 全部来源 求助全文 万方 相似文献...
United States Patent US6288062 Note: If you have problems viewing the PDF, please make sure you have the latest version ofAdobe Acrobat. Back to full text