Cystic Fibrosisis a recessive genetic disorder that affects the mucus lining of the lungs, which leads to breathing problems and other health problems. The lungs are composed of air passages, starting from the trachea (or windpipe) which divides into a left and right main bronchus, which keep ...
Cystic fibrosis (CF) is a genetic disease characterized by dehydration of airway surface liquid and impaired mucociliary clearance. As a result, there is d... PA Flume,PJ Mogayzel,KA Robinson,... - 《American Journal of Respiratory & Critical Care Medicine》 被引量: 1120发表: 2009年 Effe...
The mutation that affects a gene in the chromosome 7's long arm that specifically converts for the cystic fibrosis transmembrane regulator (CTFR) protein is the common genetic abnormality. Furthermore, it can also cause men's infertility and women's sub-fertility. The task to perform in ...
CYSTIC FIBROSIS (CF) is a hereditary disease in which there is a generalized abnormality of the function of the exocrine glands. 1 It is now recognized that in addition to the pancreas, there may be involvement of the respiratory tract, ... O Efrati,A Barak,Y Bujanover,... 被引量: 0...
The Lung Institute of WA (LIWA) has recently made a breakthrough in the search for a drug to improve the quality of life of patients with Cystic Fibrosis (CF).
Cystic fibrosis (CF) was first described as a disease in the late 1930s. It is the most common genetic disease among people with European ancestry. Approximately one in every 25 people of European descent is a carrier for the cystic fibrosis gene, having one normal gene and one CF gene. ...
Cystic fibrosis is also a genetic disease associated with intense neutrophilic inflammation in the airways leading to a fibro-cystic degeneration of the lung parenchyma. Decreased exhaled NO concentrations are seen in this disease, but the measurement of exhaled NO has a limited role in the monitorin...
Cystic fibrosis (CF) is characterized by an abnormality in cAMP-regulated chloride transport that results from a primary defect in the protein product of t... CR Marino,LM Matovcik,FS Gorelick,... - 《Journal of Clinical Investigation》 被引量: 1713发表: 1991年 Localization of the cystic ...
Cystic fibrosis is an autosomal recessive, monogenetic disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The gene defect was first described 25 years ago and much progress has been made since then in our
CYSTIC FIBROSIS (CF) is an autosomal recessive genetic disorder with a frequency of about 1/1,600 among newborn infants of European descent. In spite of extensive investigation its primary molecular abnormality remains unknown. It has been observed that most CF patients lack an α 2 macroglobulin...