As the processing mechanism of all known potyviruses involves the activity of cysteine proteinases, we asked whether constitutive expression of a rice cysteine proteinase inhibitor gene could induce resistance against two important potyviruses, tobacco etch virus (TEV) and potato virus Y (PVY), in ...
Cysteine proteinasesutilize thesulfhydryl groupof Cys as anucleophile. Similar toserine proteinasesa proton donor from His form a catalytic dyad (and in some cases triads) required forendopeptidaseactivity (Table 28.1). Cysteine proteinase represent a large, diverse group of plant and animalenzymeswith...
In recent years, the signaling role by mammalianproteinaseshas become evident, however, this function has been mostly attributed toserineproteinases. Of the manyisoformsof the mammalian cysteine proteinasecathepsin, it is proposed that isoforms B and L might be involved in ulcerogenic and carcinogenic...
A cysteine proteinase characterized in that it is immunologically distinct, has a molecular mass of about 25,000 and has a distinct net charge is disclosed. Ananain and comosain are such enzymes, which may be distinguished by their specificities for certain synthetic substrates. A process for the...
SCC also showed elevation of cysteine proteinase inhibitor activity and M r 13,000 and M r 82,000 inhibitors were purified. M r 13,000 inhibitor was found to have biochemical properties which were the same as those of the inhibitor present in normal skin. M r 82,000 inhibitor was not ...
2001: Bombyx cysteine proteinase inhibitor (BCPI) homologous to propeptide regions of cysteine proteinases is a strong, selective inhibitor of cathepsin L-like cysteine proteinases Journal of Biochemistry 130(6): 857-863 León-Félix, J.; Ortega-López, J.; Orozco-Solís, R.; Arroyo, R. 2004...
These data suggest that this protein-proteinase inhibitor can play a physiological role in the regulation of free cathepsin H.关键词: α2-Cysteine proteinase inhibitor Cathepsin H Kinetic study Physiological role DOI: 10.1016/0014-5793(84)80045-9 ...
展开 关键词: PROTEINASE K NATURALLY OCCURRING INHIBITOR ENZYME-INHIBITOR COMPLEX MICRODIALYSIS CRYSTAL DOI: 10.1006/bbrc.1994.1695 被引量: 10 年份: 1994 收藏 引用 批量引用 报错 分享 全部来源 免费下载 求助全文 全文购买 Elsevier 万方医学 dx.doi.org NCBI NCBI 查看更多 相似文献 参考文献 引证文献Disul...
Corn kernel cysteine proteinase inhibitor as a novel cystatin superfamily member of plant origin. Molecular cloning and expression studies Eur. J. Biochem., 209 (3) (1992), pp. 933-937 Crossref View in Scopus Google Scholar Abrahamson et al., 2003 ...
For the panpapain-like cysteine proteinase inhibitor, E-64, the ka value (s−1μm−1) for rEhCP4 was 0.017, and the value for rEhCP1 was 0.00026. To demonstrate that WRR605 bound intracellular EhCP4, we used BODIPY-labeled WRR605 in localization experiments. BODIPY-WRR605 co-...