CYP2D6*4 Reference Standard询价 产品描述 产品数据库 CBPA0083 Format Genomic DNA Description CYP2D6, cytochrome P450 family 2 subfamily D member 6, is a member of the cytochrome P450 family of monooxygenases that catalyzes drug metabolism (PMID: 28480783). CYP2D6 variants have been associated ...
名称CYP2D6*4 Reference Standard 型号CBPA0004 报价 特点CYP2D6*4 Reference Standard 详细内容 CBPA0004 FormatGenomic DNA DescriptionCYP2D6, cytochrome P450 family 2 subfamily D member 6, is a member of the cytochrome P450 family of monooxygenases that catalyzes drug metabolism (PMID: 28480783). CYP2D6...
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CYP2D6 gene is located on chromosome 22q13.1.The most frequent inactivating mutation among Caucasians is the splice site G1934A transition (CYP2D6*4 allele) that cause a truncated protein. G to A transition at the intron3/exon4 boundary of the CYP2D6 gene leads to incorrect splicing of ...
CYP2D6基因检测是指通过检测cytochrome P450 2D6 (CYP2D6)基因,来确定药物代谢的速度和效果的检测。CYP2D6是一种脂质合成酶,是药物代谢的重要分子,它可以转化大多数类精神类和抗病毒药物,从而决定药物的有效性和效果。 CYP2D6基因检测是个小分子筛查技术,可以发现在某一特定基因当中特定等位基因变异发生的情况。根据...
Objective The objective of this study is to investigate the association between CYP2D6*4, CYP3A5*3 and ABCB1 3435T polymorphisms and drug-related falls. Method Multivariate logistic regression was performed in an existing database in order to study the association between falls history and CYP2D6...
DPWG指出,在抗精神病药物治疗前进行基因分型,可根据阿立哌唑、依匹哌唑、氟哌啶醇、匹莫齐特、利培酮和珠氯噻醇与CYP2D6的相互作用以及喹硫平与CYP3A4的相互作用等,进行个体化用药方案的调整。 安智因精神神经系统个体化用药基因检测项目介绍 安智因推出了基于MassARRAY核酸质谱分析系统的精神神经系统个体化用药基因检测项...
《五种天然黄酮类成分与CYP3A4和CYP2D6相互作用的研究》一、引言黄酮类化合物是一类广泛存在于自然界中的天然化合物,具有多种生物活性,包括抗氧化、抗炎、抗肿瘤等作用。近年来,随着人们对健康和天然药物的关注度不断提高,黄酮类成分在医药、保健等领域的应用也日益广泛。CYP3A4和CYP2D6是人体内重要的药物代谢酶,...
Aim:The aim of this study was to investigate the associations between theCYP2D6*4polymorphism, interindividual differences inCYP2D6activity and adverse drug effects in postherpetic neuralgia (PHN) patients receiving tramadol.Patients & methods:The study comprised 158 patients (including 78 nonresponders ...
1.黄芩素与CYP3A4和CYP2D6的相互作用:研究表明,黄芩素能够抑制CYP3A4的活性,进而影响某些底物的代谢。同时,黄芩素还能与CYP2D6相互作用,增强其代谢能力。 2.槲皮素与CYP3A4的相互作用:槲皮素对CYP3A4具有诱导作用,可提高其活性,从而加速某些药物的代谢。 3.芦丁与CYP3A4和CYP2D6的相互作用:芦丁主要与CYP3A4相...