Alkylation of benzene can be accomplished using an alkene such as propene and an acid catalyst. Identify the electrophile and the product. 13.22 Write the structure of the product formed by alkylation of p-methylanisole using 2-methyl-l-propene and sulfuric acid. 13.23 Reaction of toluene with ...
3B). In addition, due to the rigid bicyclic nature of the [2]-ladderane, the cross-coupling proceeded with good diastereoselectivity for incorporation of the substituent on the exo-face. The incorporation of alkyl (22)37, aryl (23)15 and alkynyl (24)38 units could all be achieved. ...
this radical is preferably straight-chain and halogen is preferably F or Cl. In the case of polysubstitution, halogen is preferably F. The resultant radicals also include perfluorinated radicals. In the case of monosubstitution, the fluorine or chlorine substituent can be in any desired...
however, you realize that it’s not necessarily the size of the carbon atom itself but thehydrogensof CH3interacting with the axial hydrogens on the ring that lead to strain. Oxygen
2 /Pd, R 1N HC R (XVIII) (XIX) Ketal (XVI) is treated with a dehydrating agent such as Burgess' reagent, in an organic 15 solvent such as ether, THF or dioxane, at a temperature in the range of about 0 'C to about 25 'C, to yield the corresponding alkene (XVII). Alkene (...