(1997). A family of cyclin-like proteins that inter- act with the Pho85 cyclin-dependent kinase. Mol. Cell. Biol. 17, 1212- 1223.Measday, V., L. Moore, R. Retnakaran, J. Lee, M. Donoviel et al., 1997 A family of cyclin-like proteins that interact with the Pho85 cyclin-...
The Speedy/RINGO family of proteins are novel regulators of the cell cycle, capable of activating the cyclin-dependent kinases (Cdks) independent of cyclin binding and phosphorylation within the Cdk T-loop [1]. The human Speedy/RINGO homolog, herein referred to as Spy1, is constitutively expres...
Abstract: In eukaryotes, F-box proteins are one of the main components of the SCF complex that belongs to the family of ubiquitin E3 ligases, which catalyze protein ubiquitination and maintain the balance between protein synthesis and degradation. In the present study, we clarifi...
et al. A family of human cdc2-related protein kinases. EMBO J. 11, 2909–2917 (1992). CAS PubMed PubMed Central Google Scholar Tsai, L. H., Takahashi, T., Caviness, V. S. Jr. & Harlow, E. Activity and expression pattern of cyclin-dependent kinase 5 in the embryonic mouse ...
Vascular implications of the Kruppel-like family of transcription factors. Arterioscler Thromb Vasc Biol 2005; 25: 1135−41. 25 Suzuki T, Sawaki D, Aizawa K, Munemasa Y, Matsumura T, Ishida J, et al. Kruppel-like factor 5 shows proliferation-specific roles in vascular remodeling, direct ...
We have cloned two novel, alternatively spliced messages of human cyclin D-binding Myb-like protein (hDMP1). The known, full-length protein has been named hDMP1α and the new isoforms, hDMP1β and hDMP1γ. The hDMP1α, -β, and -γ splice variants have unique expression patterns in ...
Firstly, it possesses a protein kinase domain which resembles that of Nek1, CDK2, Plk and Tsk-1. Considering the absence of the PSTAIR motif in GAK, it is evident that GAK does not belong to the CDK family. Secondly, it harbors two putative dinucleotide-binding motifs in the kinase ...
Our results suggest that Arabidopsis CYCA3;1 and CYCA3;2 are distinct members of the G1 cyclin family that play an important role in meristematic tissues.doi:10.1007/s00299-010-0817-9Ikuo TakahashiShoko KojimaNorihiro SakaguchiChikage Umeda-Hara...
The protein microsequence shows homology toward the Pho85/CDK5 clade of CDKs. Neither the amount nor the phosphorylation state changed over the course of the cell cycle, in agreement with results reported for CDK5 family members in other systems.Conclusions. We conclude we have probably isolated ...
The protein microsequence shows homology toward the Pho85/CDK5 clade of CDKs. Neither the amount nor the phosphorylation state changed over the course of the cell cycle, in agreement with results reported for CDK5 family members in other systems. Conclusions. We conclude we have probably isolated...