Dupont J, Karas M, LeRoith D 2003 The cyclin-dependent kinase inhibitor p21CIP/WAF is a positive regulator of insulin-like growth factor I-induced cell proliferation in MCF-7 human breast cancer cells. J Biol Chem. 278:37256-37264.
The Cyclin-dependent Kinase Inhibitor p21CIP/WAF Is a Positive Regulator of Insulin-like Growth Factor I-induced Cell Proliferation in MCF-7 Human Breast C... To study the role of IGF-I receptor signaling on cell cycle events we utilized MCF-7 breast cancer cells. IGF-I at physiological co...
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On chromosome 11p15.5, deregulation of imprinted gene expression in the BWS phenotype can involve one or more of the following genes: insulin-like growth factor 2 (IGF2), H19, cyclin-dependent kinase inhibitor 1C (CDKN1C), potassium channel voltage-gated KQT-like subfamily member 1 (KC...
(15) showed that a weak overexpression of the Arabidopsis CDK inhibitor KRP2 inhibited only the mitotic cell cycle-specific CDKA;1 kinase complexes, whereas the endoreduplication cycle-specific CDKA;1 complexes were unaffected. This led to an expected increase in the DNA ploidy level. This study...
securin and mitotic cyclins, whereas CRL1(Skp2) allows entry into S phase by targeting the destruction of the cyclin-dependent kinase (CDK) inhibitor p... CG Havens,JC Walter - 《Genes & Development》 被引量: 207发表: 2011年 PP2A-B56 binds to Apc1 and promotes Cdc20 association with th...
cyclin-dependent kinase inhibitor/-s ctDNA: circulating tumor DNA EGFR: epithelial growth factor receptor ER: estrogen receptor GBM: glioblastoma multiforme HNSCC: head and neck squamous cell carcinoma HPV: human papillomavirus HR: homologous recombination iASPP: inhibitor of apoptosis-stimulat...
Kinase assay. HEK293 cells were transfected with expression vectors and lysed in ice-cold lysis buffer consisting of 150 mM NaCl, 50 mM Tris at pH 7.5, 1% (vol/vol) Triton X-100, 1 mM PMSF, and 1× protease inhibitor cocktail (Roche). The supernatant was collected and ...
Cyclin-dependent kinase inhibitor, flavopiridol, induces apoptosis and inhibits tumor growth in drug-resistant osteosarcoma and Ewing's family tumor cells. Int J Cancer 2007;121(6):1212-8.Li Y, Tanaka K, Li X. Cyclin-dependent kinase inhibitor, flavopiridol, induces apoptosis and inhibits tumor ...
Evaluation of Cyclin-Dependent Kinase-Like 1 Expression in Breast Cancer Tissues and Its Regulation in Cancer Cell Growth.Evaluation of Cyclin-Dependent Kinase-Like 1 Expression in Breast Cancer Tissues and Its Regulation in Cancer Cell Growth.Cyclin-dependent kinase-like 1 (CDKL1) is a member of...